Description

Acnetin (Isotretinoin) Capsules 16 mg. №30

Composition

Each capsule contains 16 mg of isotretinoin.

Mechanism of Action

Isotretinoin works by targeting the sebaceous glands, reducing sebum production, and exerting anti-inflammatory effects, thereby improving acne symptoms.

Pharmacological Properties

Isotretinoin is a retinoid that regulates cell proliferation, differentiation, and apoptosis. It normalizes follicular keratinization and reduces inflammation in acne lesions.

Indications for Use

Acnetin capsules are specifically indicated for the treatment of severe recalcitrant nodular acne that has not responded to other therapies.

Contraindications

Avoid using Acnetin capsules if pregnant, planning pregnancy, breastfeeding, or hypersensitive to isotretinoin. It is crucial to use effective contraception during treatment due to teratogenic effects.

Side Effects

Common side effects of Acnetin capsules include dry skin, lips, and eyes, photosensitivity, and musculoskeletal symptoms. Regular monitoring is necessary to address any adverse reactions promptly.

Usage Instructions

Take Acnetin capsules as prescribed by a healthcare provider, usually with a meal to enhance absorption. It is recommended to drink a full glass of water with each dose.

Benefits Compared to Analogues

Acnetin capsules offer superior efficacy in treating severe nodular acne compared to other conventional therapies. The targeted mechanism of action helps achieve better outcomes with a lower risk of antibiotic resistance.

Suitable Patient Groups

Acnetin capsules are suitable for adolescents and adults with severe nodular acne who have not responded to topical treatments. Special caution is advised for females of childbearing potential due to the teratogenic potential.

Storage and Shelf Life

Store Acnetin capsules at room temperature away from moisture and heat. Check the expiration date on the packaging and do not use expired medication.

Packaging Description

Acnetin capsules are packaged in a container with 30 capsules, each containing 16 mg of isotretinoin. The packaging is designed to maintain the stability and integrity of the capsules.

Clinical Evidence and Proven Effectiveness

Scientific studies have demonstrated the efficacy of isotretinoin in treating severe acne, particularly nodular forms. Clinical trials have shown significant reductions in lesion counts, sebum production, and inflammatory markers with isotretinoin therapy.