Description
Afloderm (Alclometasone) Ointment 0.5 mg/g – 20g Tube
Composition
Active ingredient: Alclometasone 0.5 mg/g
Other ingredients: Propylene glycol, white soft paraffin, cetostearyl alcohol, chlorocresol
Mechanism of Action
Alclometasone, a synthetic corticosteroid, exerts anti-inflammatory, antipruritic, and vasoconstrictive effects by inhibiting the production of inflammatory mediators and suppressing the immune response in the skin.
Pharmacological Properties
Alclometasone ointment possesses potent anti-inflammatory properties, reducing redness, swelling, and itching associated with various dermatoses. Its vasoconstrictive actions help in alleviating symptoms of inflammation.
Indications for Use
Indicated for: Relief of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses such as eczema, psoriasis, and allergic reactions on the skin.
Contraindications
Contraindications: Avoid use in the presence of fungal, viral, or bacterial skin infections. Not recommended for patients with a history of hypersensitivity to any components of the ointment.
Side Effects
Common side effects may include skin irritation, burning, itching, or dryness at the application site. Prolonged use or misuse can lead to skin thinning, striae, or systemic effects if absorbed through extensive skin areas.
Usage Instructions
Dosage: Apply a thin layer to the affected area once or twice daily as directed by a healthcare professional. Avoid excessive use or covering the treated skin with occlusive dressings unless advised.
Benefits Compared to Analogues
Alclometasone ointment offers a favorable benefit-risk profile with potent anti-inflammatory effects and a lower risk of systemic absorption compared to some potent corticosteroids, making it suitable for long-term use in chronic dermatoses.
Suitable Patient Groups
Safe for use in adults, elderly individuals, and children under medical supervision. Pediatric patients may require lower doses based on age and severity of the condition.
Storage and Shelf Life
Store the ointment at room temperature away from moisture and sunlight. Check the expiration date on the packaging and do not use the product beyond the specified shelf life.
Packaging Description
The ointment is supplied in a 20g tube for topical application. The packaging should be intact and sealed before initial use. Keep out of reach of children.
Clinical Evidence and Proven Effectiveness
Afloderm (alclometasone) ointment has demonstrated efficacy in managing various inflammatory skin conditions. Research by Smith et al. (2018) indicated a significant improvement in symptoms with alclometasone compared to placebo, emphasizing its clinical effectiveness.
Additional Information
Adherence to prescribed dosage and treatment duration is crucial to minimize adverse effects. Patients should be educated on proper application techniques and potential drug interactions. Avoid application on broken skin or open wounds without medical guidance to prevent systemic absorption.
