Description
Aladin (amlodipine besylate) Tablets 5 mg. №30
Composition
Active Ingredient: Amlodipine besylate 5 mg.
Mechanism of Action
Amlodipine is a calcium channel blocker that works by relaxing blood vessels, thereby facilitating the heart’s pumping action. This action reduces blood pressure and enhances blood circulation, consequently easing the heart’s workload.
Pharmacological Properties
Amlodipine, the active component of Aladin, exerts its effects by selectively blocking calcium channels in vascular smooth muscle and cardiac muscle. By inhibiting calcium influx, it leads to vasodilation and improved oxygen delivery to the heart muscle.
Indications for Use
Indications: Aladin is indicated for the management of hypertension to control blood pressure levels and for the treatment of chronic stable angina to alleviate chest pain and improve exercise tolerance.
Contraindications
Contraindications: Aladin should not be administered to individuals with a known hypersensitivity to amlodipine or any other tablet components. Patients with severe hypotension or cardiogenic shock should also avoid its use.
Side Effects
Common side effects of Aladin may include peripheral edema, headache, dizziness, and fatigue. In rare cases, more severe adverse effects like hypotension, palpitations, and allergic reactions may occur. Consult a healthcare professional if any adverse reactions are experienced.
Usage Instructions
Dosage: The standard initial dosage of Aladin is 5 mg once daily. Depending on individual response, the dose can be titrated up to a maximum of 10 mg once daily. The tablets should be swallowed whole with a glass of water, with or without food.
Benefits Compared to Analogues
Aladin offers the advantage of once-daily dosing convenience compared to some other antihypertensive medications. Its efficacy in managing hypertension and angina has been well-established through clinical trials, making it a preferred choice for many healthcare providers.
Suitable Patient Groups
Aladin is suitable for adult patients, including the elderly, who require treatment for hypertension or chronic stable angina. It is not recommended for use in children or adolescents due to limited safety and efficacy data in this population.
Storage and Shelf Life
Store Aladin tablets in a cool, dry place away from direct sunlight and moisture. Ensure the packaging is tightly closed to protect the tablets from air and humidity. Check the expiration date on the packaging and do not use the tablets beyond this date.
Packaging Description
Aladin tablets are typically packaged in blister packs to maintain product integrity and protect them from environmental factors. Each pack contains 30 tablets of amlodipine besylate 5 mg strength.
Clinical Evidence and Proven Effectiveness
Pharmacological Effects: Amlodipine’s calcium channel blocking properties have been extensively studied and proven effective in managing hypertension and angina by enhancing blood flow and reducing vascular resistance.
Clinical Studies: Research published in the Journal of the American College of Cardiology demonstrated that amlodipine significantly reduces the incidence of cardiovascular events in hypertensive patients. Multiple trials have shown its efficacy in improving cardiovascular outcomes.
Additional Information
It is crucial to adhere to the prescribed regimen when using Aladin. Abrupt discontinuation of the medication can lead to rebound hypertension; therefore, consult your healthcare provider before making any changes to your treatment plan. Avoid grapefruit products while taking Aladin to prevent potential drug interactions.
