Description

Ampril HD Tablets 5 mg/25 mg – Box of 30 Tablets

Composition

Each tablet contains 5 mg of Ramipril and 25 mg of Hydrochlorothiazide.

Mechanism of Action

Ramipril inhibits the angiotensin-converting enzyme, leading to vasodilation and reduced aldosterone secretion. Hydrochlorothiazide acts on the kidneys to increase the excretion of sodium and water, reducing blood volume and lowering blood pressure.

Pharmacological Properties

Ampril HD tablets combine the effects of an ACE inhibitor and a diuretic to effectively reduce blood pressure levels.

Indications for Use

Ampril HD tablets are indicated for the treatment of hypertension when blood pressure is not adequately controlled by ramipril or hydrochlorothiazide monotherapy.

Contraindications

Avoid using Ampril HD tablets if allergic to any ingredients, have a history of angioedema related to ACE inhibitor therapy, or severe renal impairment.

Side Effects

Common side effects may include dizziness, cough, and electrolyte imbalances. Contact your healthcare provider if experiencing severe side effects.

Usage Instructions

The usual recommended dose is one tablet daily, to be taken with or without food as directed by your healthcare provider.

Benefits Compared to Analogues

Studies have shown that the combination of ramipril and hydrochlorothiazide is more effective in reducing blood pressure compared to monotherapy.

Suitable Patient Groups

Ampril HD tablets are suitable for adult patients with hypertension. Dosage adjustments may be necessary for specific patient populations like the elderly.

Storage and Shelf Life

Store in a cool, dry place away from sunlight. Check the expiration date on the packaging and do not use after the specified date.

Packaging Description

Each box contains 30 tablets of Ampril HD, each tablet individually sealed for protection.

Clinical Evidence and Proven Effectiveness

Ramipril and hydrochlorothiazide combination significantly reduces systolic and diastolic blood pressure levels, as demonstrated in studies published in reputable medical journals.