Description

Atenolol Tablets 50 mg. №20

Composition

Each tablet contains 50 mg of atenolol.

Mechanism of Action

Atenolol is a beta-blocker that selectively blocks beta-1 adrenergic receptors, leading to reduced heart rate, cardiac output, and blood pressure.

Pharmacological Properties

Atenolol exerts its antihypertensive and antianginal effects by reducing sympathetic nervous system activity and inhibiting renin-angiotensin-aldosterone system activation.

Indications for Use

Atenolol is indicated for the management of hypertension, stable angina pectoris, and as an adjunct in the early treatment of acute myocardial infarction to reduce cardiovascular mortality.

Contraindications

Avoid using atenolol in patients with bradycardia, heart block greater than first degree, cardiogenic shock, decompensated heart failure, or severe peripheral arterial circulatory disorders.

Side Effects

Common side effects of atenolol include bradycardia, hypotension, dizziness, fatigue, and cold extremities. Rarely, serious adverse reactions such as bronchospasm and heart block may occur.

Usage Instructions

The typical starting dose of atenolol is 50 mg once daily. Dosage adjustments should be made based on individual response and tolerability. It is essential not to discontinue atenolol abruptly without medical guidance.

Benefits Compared to Analogues

Atenolol offers comparable efficacy to other beta-blockers in managing hypertension and angina. Its advantage lies in its long-term safety profile and established cardiovascular benefits in specific patient populations.

Suitable Patient Groups

Atenolol is generally well-tolerated in adults, including the elderly population. However, caution is advised when using atenolol in pediatric patients due to limited data on safety and efficacy in this age group.

Storage and Shelf Life

Store atenolol tablets in a cool, dry place away from moisture and sunlight. Check the expiration date on the packaging and do not use the product beyond the stated shelf life.

Packaging Description

Each package contains 20 tablets of atenolol 50 mg. The tablets are typically blister-packed to ensure individual dosage unit integrity.

Clinical Evidence and Proven Effectiveness

Atenolol has been extensively researched in numerous clinical trials. Studies have demonstrated its efficacy in reducing blood pressure, preventing cardiovascular events, and improving outcomes in patients with various cardiovascular conditions.