Description
Augmentin (Amoxicillin Sodium) Powder for Suspension 228.5 mg/5 ml. 70 ml
Ingredients
Each 5 ml of reconstituted suspension contains 228.5 mg of amoxicillin (as amoxicillin sodium) and 57 mg of clavulanic acid (as potassium clavulanate).
Mechanism of Action
Augmentin is a combination of amoxicillin and clavulanic acid. Amoxicillin inhibits bacterial cell wall synthesis, while clavulanic acid inhibits bacterial beta-lactamases, enzymes that can inactivate antibiotics. This dual action helps combat a wide range of bacterial infections.
Pharmacological Properties
The pharmacological properties of Augmentin stem from the synergistic effects of amoxicillin and clavulanic acid. This combination extends the spectrum of activity against many bacteria, including those resistant to other antibiotics.
Indications for Use
Augmentin is indicated for the treatment of various bacterial infections, such as respiratory tract infections, urinary tract infections, skin and soft tissue infections, otitis media, and sinusitis. It is effective against both Gram-positive and Gram-negative bacteria.
Contraindications
Avoid using Augmentin if you have a history of allergic reactions to penicillin or cephalosporin antibiotics. Consult your healthcare provider for alternative treatment options if you have known allergies to these antibiotic classes.
Side Effects
Common side effects of Augmentin may include gastrointestinal disturbances, such as diarrhea, nausea, and vomiting. Allergic reactions like skin rash and itching may occur. In rare cases, severe side effects like liver dysfunction or pseudomembranous colitis can occur. Contact your doctor if you experience any adverse effects.
Usage Instructions
Prior to administration, shake the bottle well to ensure proper reconstitution of the suspension. Use a specialized measuring spoon or cup to accurately measure the prescribed dose. Take Augmentin orally with food, as directed by your healthcare provider.
Benefits Compared to Analogues
Augmentin offers a distinct advantage over other antibiotics due to its dual mechanism of action. The combination of amoxicillin and clavulanic acid provides broader coverage against bacterial strains, including those resistant to traditional penicillins.
Suitable Patient Groups
Augmentin is suitable for use in both adults and children, under appropriate medical supervision. Dosage adjustments may be necessary in elderly patients or individuals with impaired renal function. Consult a healthcare professional for personalized dosing recommendations.
Storage and Shelf Life
Store Augmentin suspension in a cool, dry place away from direct sunlight. Follow the instructions on the packaging regarding storage temperature requirements. Check the expiration date on the label and do not use the product beyond the specified shelf life.
Packaging Description
Augmentin is supplied as a powder for suspension in a 70 ml bottle. The packaging includes instructions for reconstitution and dosage administration. Each bottle is labeled with the active ingredients and concentration for accurate dosing.
Scientific Evidence
Augmentin, through clinical studies, has demonstrated efficacy in treating various bacterial infections. Its ability to combat resistant bacterial strains has been attributed to the presence of clavulanic acid, which enhances the activity of amoxicillin. Consult your healthcare provider for more information on the clinical evidence supporting Augmentin’s effectiveness.
