Description
Cardosal (Olmesartan Medoxomil) Coated Tablets 10 mg. №28
Composition
The active ingredient in Cardosal is olmesartan medoxomil, a medication used to treat high blood pressure. Each tablet contains 10 mg of olmesartan medoxomil.
Mechanism of Action
Olmesartan medoxomil is an angiotensin II receptor blocker (ARB) that works by blocking the action of angiotensin II, a substance in the body that causes blood vessels to constrict. By blocking the effects of angiotensin II, olmesartan medoxomil helps relax and widen blood vessels, lowering blood pressure.
Pharmacological Properties
Olmesartan medoxomil is rapidly and completely converted to its active form, olmesartan, in the body. It selectively inhibits the binding of angiotensin II to the angiotensin II receptor, leading to vasodilation and decreased secretion of aldosterone.
Indications for Use
Cardosal is indicated for the treatment of high blood pressure (hypertension). It is beneficial in reducing the risk of cardiovascular events such as strokes, heart attacks, and renal complications in hypertensive patients.
Contraindications
Cardosal is contraindicated in patients with hypersensitivity to olmesartan medoxomil or any other component of the product. It should not be used in pregnant women, especially during the second and third trimesters, due to the risk of fetal harm. Cardosal is also contraindicated during breastfeeding.
Side Effects
Common side effects of Cardosal may include dizziness, headache, fatigue, and gastrointestinal disturbances. Rare but serious side effects may include angioedema, renal impairment, and hyperkalemia. Patients should seek medical attention if they experience any severe or persistent side effects.
Usage Instructions
Cardosal should be taken orally, with or without food. The recommended starting dose is one 10 mg tablet once daily. Dosage adjustments may be made by a healthcare provider based on individual patient response. It is important to adhere to the prescribed dosing regimen and take Cardosal at the same time each day.
Benefits Compared to Analogues
Cardosal offers the advantage of once-daily dosing, providing convenient and effective blood pressure control. Its active ingredient, olmesartan medoxomil, has demonstrated superior efficacy in lowering blood pressure compared to some other ARBs. Additionally, Cardosal has a favorable side effect profile, making it well-tolerated by many patients.
Suitable Patient Groups
Cardosal is suitable for adult patients with hypertension who require blood pressure management. It can be used in elderly patients as well as individuals with certain comorbidities such as diabetes or chronic kidney disease. However, special caution should be exercised when prescribing Cardosal to pregnant women, children, and individuals with severe hepatic impairment.
Storage and Shelf Life
Cardosal should be stored at room temperature away from moisture and heat. The tablets should be kept in their original packaging to protect them from light. The shelf life of Cardosal is typically indicated on the packaging and should be checked before use to ensure the medication is within its expiration date.
Packaging Description
Cardosal is available in blister packs containing 28 coated tablets of 10 mg strength each. The packaging is designed to maintain the stability and integrity of the tablets, ensuring their quality and potency until the expiration date.
