Description
Carvedilol (Carvedilol) Tablets 12.5 mg. №30
Composition
The active ingredient in Carvedilol tablets is Carvedilol, with each tablet containing 12.5 mg of Carvedilol.
Mechanism of Action
Carvedilol is a non-selective beta-blocker with alpha-blocking activity. It works by blocking beta-adrenergic receptors and inhibiting the action of the sympathetic nervous system, leading to a reduction in heart rate, blood pressure, and cardiac workload.
Pharmacological Properties
Carvedilol exhibits anti-hypertensive, anti-arrhythmic, and anti-ischemic properties. It also has antioxidant effects and can improve cardiac function in heart failure patients.
Indications for Use
Carvedilol tablets are indicated for the treatment of hypertension, heart failure, and post-myocardial infarction to improve survival rates and reduce the risk of cardiovascular events.
Contraindications
- Carvedilol is contraindicated in patients with severe liver impairment due to its metabolism in the liver.
- Patients with certain types of heart rhythm disorders, such as severe bradycardia or heart block, should not use Carvedilol.
- Individuals with known hypersensitivity to Carvedilol or any of its components should avoid its use.
Side Effects
Common side effects of Carvedilol may include dizziness, fatigue, hypotension, bradycardia, and gastrointestinal disturbances. Rare but serious side effects may include bronchospasm, heart failure exacerbation, and liver toxicity.
Usage Instructions
Carvedilol tablets should be taken orally with food to enhance absorption and minimize gastrointestinal discomfort. The typical recommended dose is 12.5 mg once or twice daily, as prescribed by a healthcare provider.
Advantages Over Analogues
Carvedilol offers a dual mechanism of action as a beta-blocker and alpha-blocker, providing comprehensive cardiovascular protection compared to traditional beta-blockers. Its antioxidant properties further distinguish it from other medications in heart failure management.
Suitable Patient Groups
Carvedilol is suitable for adult patients with hypertension, heart failure, or a history of myocardial infarction. It may also be used in pediatric patients with specific cardiac conditions under the guidance of a pediatric cardiologist.
Storage and Shelf Life
Carvedilol tablets should be stored at room temperature away from moisture and heat. The shelf life of the product is typically stated on the packaging and should be adhered to for optimal efficacy.
Packaging Description
The Carvedilol tablets are typically packaged in blister packs or amber-colored bottles to protect them from light degradation. Each package contains 30 tablets of 12.5 mg strength.
