Description
Cefix (Cefixime) Suspension Powder 100 mg/5 ml – 30 ml
Composition
The active ingredient in Cefix is cefixime, a third-generation cephalosporin antibiotic. Each 5 ml of the suspension contains 100 mg of cefixime.
Mechanism of Action
Cefixime inhibits bacterial cell wall synthesis by binding to specific penicillin-binding proteins, resulting in the inhibition of peptidoglycan cross-linking. This leads to bacterial cell death.
Pharmacological Properties
Cefixime demonstrates broad-spectrum activity against gram-positive and gram-negative bacteria. It is stable in the presence of beta-lactamases, enhancing its efficacy against resistant strains.
Indications for Use
Cefix is indicated for the treatment of otitis media, sinusitis, urinary tract infections, and uncomplicated gonorrhea caused by susceptible organisms.
Contraindications
Cefix is contraindicated in patients with a known allergy to cefixime or other cephalosporins. It should be used with caution in patients with severe renal impairment, requiring dose adjustment based on renal function.
Side Effects
Common side effects of Cefix may include gastrointestinal disturbances, allergic reactions, and skin rash. Severe adverse effects such as pseudomembranous colitis and anaphylaxis are rare but possible.
Usage Instructions
Cefix suspension is administered orally. Shake the bottle well before each use to ensure homogeneity. Use the provided measuring device for accurate dosing.
- For optimal outcomes, maintain regular intervals between doses.
- Complete the full prescribed course even if symptoms resolve early.
- Discontinuing treatment prematurely may lead to recurrence of the infection.
Benefits Compared to Analogues
Cefixime offers advantages over some analogues due to its broad spectrum of activity, stability against beta-lactamases, and convenient oral suspension formulation for ease of administration.
Suitable Patient Groups
Cefix can be used in various patient populations, including children and adults. Dosing adjustments may be necessary based on age, weight, and renal function.
Storage and Shelf Life
Store Cefix suspension in a cool, dry place away from direct sunlight. Check the expiration date on the packaging and do not use the product beyond this date.
Packaging Description
Cefix suspension is available in a 30 ml bottle containing 100 mg of cefixime per 5 ml. The packaging includes a measuring device for accurate dosing.
