Description
Cefoperazon Plus (Cefoperazone) Powder for Injections 1g/1g. №1
Composition
The primary active component in Cefoperazon Plus is cefoperazone, a potent broad-spectrum antibiotic belonging to the cephalosporin class.
Mechanism of Action
Cefoperazone exerts its antibacterial effect by inhibiting bacterial cell wall synthesis, leading to cell death. It acts by binding to penicillin-binding proteins, disrupting the cross-linking of peptidoglycans in the cell wall.
Pharmacological Properties
Cefoperazon Plus demonstrates excellent bactericidal activity against a wide range of Gram-positive and Gram-negative bacteria. It has a long half-life, allowing for less frequent dosing intervals.
Indications for Use
Cefoperazon Plus is indicated for treating infections caused by susceptible bacteria, including:
- Respiratory tract infections
- Urinary tract infections
- Skin and soft tissue infections
- Bone and joint infections
- Gynecologic infections
- Intra-abdominal infections
Contraindications
Cefoperazon Plus is contraindicated in individuals with a history of hypersensitivity to cefoperazone or other cephalosporin antibiotics due to the risk of severe allergic reactions.
Side Effects
Common side effects of Cefoperazon Plus may include gastrointestinal disturbances, hypersensitivity reactions, and superinfections. Monitoring for adverse effects is crucial during treatment.
Usage Instructions
Cefoperazon Plus should be administered via intravenous or intramuscular injection after reconstitution with sterile water for injection. Dosage and administration should be tailored to the specific infection and patient’s condition as directed by a healthcare professional.
Advantages Over Analogues
Cefoperazon Plus offers the advantage of broader antibacterial coverage compared to some cephalosporins, making it effective against a wider range of pathogens. Its extended half-life allows for convenient dosing schedules.
Suitable Patient Groups
Cefoperazon Plus is suitable for use in both pediatric and adult populations, including elderly patients. Dosing adjustments may be necessary based on renal function in elderly individuals.
Storage and Shelf Life
Cefoperazon Plus should be stored in a cool, dry place away from direct sunlight. The product has a shelf life of [insert shelf life here] and should not be used beyond the expiration date.
Packaging Description
Cefoperazon Plus is supplied as a powder for injection in single-dose vials. Each vial contains 1g of cefoperazone for reconstitution before administration.
