Description
Cefutil (Cefuroxime) Coated Tablets 250 mg. №10
Composition
The active ingredient in Cefutil is cefuroxime, a second-generation cephalosporin antibiotic. Each tablet contains 250 mg of cefuroxime.
Mechanism of Action
Cefuroxime inhibits bacterial cell wall synthesis by binding to essential penicillin-binding proteins, resulting in cell lysis and death.
Pharmacological Properties
Cefuroxime exhibits bactericidal activity against a wide range of gram-positive and gram-negative bacteria. It is stable in the presence of many beta-lactamases.
Indications for Use
- Respiratory tract infections
- Skin and soft tissue infections
- Urinary tract infections
- Gonorrhea
Contraindications
Cefutil is contraindicated in patients with a known allergy to cephalosporin antibiotics. Caution is advised in patients with renal impairment or a history of gastrointestinal disease due to the risk of adverse reactions.
Side Effects
Common side effects of Cefutil may include gastrointestinal disturbances, allergic reactions, and superinfections. Serious adverse effects such as pseudomembranous colitis and anaphylaxis are rare but possible.
Usage Instructions
Take Cefutil tablets with food to optimize absorption. Swallow the tablets whole; do not crush or chew them. If a dose is missed, take it as soon as remembered. Do not double doses to compensate for a missed dose.
Benefits Compared to Analogues
Cefutil offers a broad spectrum of antibacterial coverage compared to some first-generation cephalosporins. Its twice-daily dosing regimen provides convenient and effective treatment for various infections.
Suitable Patient Groups
Cefutil is suitable for use in adults, including the elderly, and pediatric patients for specific indications. Dosage adjustments may be necessary based on individual patient factors.
Storage and Shelf Life
Store Cefutil in a cool, dry place away from direct sunlight. Keep the tablets in their original packaging to protect them from moisture. Check the expiration date on the packaging and do not use expired tablets.
Packaging Description
Cefutil tablets are typically packaged in blister packs of 10 tablets each. The packaging is designed to maintain the stability and integrity of the tablets until use.