Description
Centrolin (Choline Alfoscerate) Solution for Injections 1000 mg/4ml Ampoules №5
Composition
The main active ingredient in Centrolin is choline alfoscerate. Each 4ml ampoule contains 1000 mg of choline alfoscerate.
Mechanism of Action
Choline alfoscerate, the active ingredient in Centrolin, acts as a precursor of acetylcholine synthesis in the brain. It facilitates the transmission of nerve impulses and supports cognitive function.
Pharmacological Properties
Centrolin exerts its pharmacological effects by enhancing cholinergic neurotransmission in the central nervous system. It promotes neuronal membrane integrity and function, thereby improving cognitive processes.
Indications for Use
Centrolin is indicated for the treatment of cognitive disorders in adults, particularly those associated with neurodegenerative conditions such as Alzheimer’s disease and dementia.
Contraindications
Centrolin is contraindicated in patients with a known hypersensitivity to choline alfoscerate or any other component of the formulation. It should not be used in individuals with severe renal impairment due to the potential risk of adverse effects.
Side Effects
Common side effects of Centrolin may include gastrointestinal disturbances, such as nausea and diarrhea. In rare cases, allergic reactions or neurological symptoms like headaches or dizziness may occur. Patients should report any unusual or severe side effects to their healthcare provider.
Usage Instructions
The recommended dosage of Centrolin is one ampoule (1000 mg/4ml) per day, to be administered by intramuscular or intravenous injection. Healthcare professionals should supervise the administration process, ensuring a slow injection over 3-5 minutes. The solution should not be used if it appears discolored or contains particles.
Benefits Compared to Analogues
Centrolin offers a unique advantage over other cognitive enhancers by specifically targeting cholinergic pathways in the brain. Its high potency and bioavailability make it an effective choice for managing cognitive impairment associated with neurodegenerative diseases.
Suitable Patient Groups
Centrolin is suitable for adult patients experiencing cognitive decline due to conditions like Alzheimer’s disease or dementia. It is not recommended for use in children, and special caution should be exercised when prescribing to elderly individuals or those with compromised renal function.
Storage and Shelf Life
Centrolin should be stored at controlled room temperature, away from light and moisture. The product has a shelf life of [insert specific shelf life information here] and should not be used beyond the expiration date printed on the packaging.
Packaging Description
Each package of Centrolin contains 5 ampoules, with each ampoule holding 1000 mg of choline alfoscerate in a 4ml solution. The ampoules are designed for single-use and should be handled with care to prevent breakage or contamination.
