Description
Ketanov (Ketorolac Trometamine) Solution for Injections Ampoules 30 mg, 1ml, Pack of 10
Composition
The primary active ingredient in Ketanov is Ketorolac Trometamine. Each ampoule contains 30 mg of Ketorolac Trometamine in a 1 ml solution.
Mechanism of Action
Ketorolac Trometamine is a nonsteroidal anti-inflammatory drug (NSAID) that exhibits analgesic, anti-inflammatory, and antipyretic properties. It works by inhibiting the production of prostaglandins, thereby reducing pain and inflammation.
Pharmacological Properties
Ketorolac Trometamine exerts its effects by blocking the enzyme cyclooxygenase, which is involved in the synthesis of prostaglandins. This results in decreased inflammation, pain, and fever.
Indications for Use
Ketanov is indicated for the short-term management of moderate to severe acute pain. It is also recommended for use as an analgesic during diagnostic procedures and in the postoperative period.
Contraindications
- Patients with a known hypersensitivity to Ketorolac Trometamine or other NSAIDs should not use Ketanov.
- Individuals with an active or history of recurrent peptic ulcer disease or gastrointestinal bleeding are contraindicated for Ketanov use.
- Patients with severe renal impairment or at risk of renal failure due to volume depletion should avoid Ketanov.
- Use of Ketanov is contraindicated in patients in the peri-operative period during coronary artery bypass graft (CABG) surgery.
Side Effects
Common side effects of Ketanov may include gastrointestinal disturbances, nausea, vomiting, dizziness, headache, and renal impairment. Serious adverse effects such as gastrointestinal bleeding and allergic reactions may occur rarely.
Usage Instructions
Ketanov is intended for intramuscular or intravenous administration only. The recommended dosage should not exceed 60 mg per day for intramuscular use and 120 mg per day for intravenous use. The typical dosing interval is every 6 hours, not to exceed 5 days of use.
Note: Patients should strictly follow the dosage instructions provided by their healthcare provider.
Benefits Compared to Analogues
Ketanov offers rapid and effective pain relief with a lower risk of gastrointestinal side effects compared to some other NSAIDs. Its dual route of administration provides flexibility in managing pain in different clinical settings.
Suitable Patient Groups
Ketanov can be used in various patient populations including adults, elderly individuals, and adolescents for the management of acute pain. However, special caution is advised in patients with renal impairment and those at risk of gastrointestinal complications.
Storage and Shelf Life
Ketanov should be stored at room temperature, away from moisture and light. The shelf life of Ketanov ampoules is typically indicated on the packaging and should be checked before use.
Packaging Description
Ketanov is supplied in ampoules containing 30 mg of Ketorolac Trometamine in a 1 ml solution. Each pack consists of 10 ampoules for single-use administration.
Clinical Evidence and Proven Effectiveness
Clinical studies have demonstrated the efficacy of Ketanov in providing significant pain relief in various acute conditions. The drug’s fast onset of action and potent analgesic effects make it a valuable option in pain management protocols.
