Description
Ketoconazol-Fitofarm (ketoconazole) Cream 2% 15g
Composition
The active ingredient in Ketoconazol-Fitofarm cream is ketoconazole, an antifungal medication that inhibits the synthesis of ergosterol, a key component of fungal cell membranes, thereby disrupting fungal cell growth and replication.
Mechanism of Action
Ketoconazole exerts its antifungal effects by inhibiting the enzyme lanosterol 14α-demethylase, which is essential for the conversion of lanosterol to ergosterol in fungal cell membranes. This disruption leads to increased membrane permeability and ultimately fungal cell death.
Pharmacological Properties
Ketoconazole demonstrates broad-spectrum antifungal activity against various dermatophytes, yeasts, and other fungi. It also exhibits anti-inflammatory properties, contributing to the resolution of associated symptoms such as itching and redness.
Indications for Use
Ketoconazol-Fitofarm cream is indicated for the treatment of superficial fungal infections, including athlete’s foot (tinea pedis), jock itch (tinea cruris), ringworm (tinea corporis), and seborrheic dermatitis affecting the scalp (dandruff).
Contraindications
Do not use Ketoconazol-Fitofarm cream if you have a known hypersensitivity to ketoconazole or any other components of the formulation. Additionally, consult with your healthcare provider before use if you are pregnant, planning pregnancy, or breastfeeding, as the safety of ketoconazole during these conditions has not been definitively established.
Side Effects
Common side effects of Ketoconazol-Fitofarm cream may include local skin reactions such as itching, redness, or a burning sensation at the application site. In rare cases, contact dermatitis or allergic reactions may occur. If you experience severe irritation or any unexpected symptoms, discontinue use and seek medical advice.
Usage Instructions
Apply a thin layer of the cream to the affected area once or twice daily, as directed by your healthcare provider. Gently massage the cream into the skin until fully absorbed. Avoid covering or bandaging the treated area unless specifically instructed by a healthcare professional. Remember to wash your hands after application to prevent unintentional transfer of the medication.
Benefits Compared to Analogues
Ketoconazol-Fitofarm cream offers the advantage of potent antifungal activity coupled with anti-inflammatory effects, providing comprehensive treatment for fungal skin infections while addressing associated symptoms. Its broad-spectrum efficacy against various fungal species distinguishes it from some topical antifungal agents with narrower spectrums of activity.
Suitable Patient Groups
Ketoconazol-Fitofarm cream is generally safe for use in adults, including the elderly population, and in children under medical supervision. However, individual considerations and dosage adjustments may be necessary in specific patient populations, such as those with compromised liver function or certain medical conditions. Consult a healthcare provider for personalized recommendations.
Storage and Shelf Life
Store Ketoconazol-Fitofarm cream at room temperature, away from direct sunlight and moisture. Ensure the tube is tightly closed when not in use. Check the expiration date on the packaging and do not use the cream beyond the stated shelf life to maintain its efficacy and safety.
Packaging Description
Ketoconazol-Fitofarm cream is supplied in a 15g tube for topical application. The packaging should include essential information such as the product name, active ingredient concentration, directions for use, contraindications, and expiration date. Ensure proper disposal of the empty tube according to local regulations.
