Description
Hartil Tablets 5 mg. №28
Composition
The active ingredient in Hartil Tablets is Ramipril. Each tablet contains 5 mg of Ramipril.
Mechanism of Action
Ramipril, the active ingredient in Hartil Tablets, is an angiotensin-converting enzyme (ACE) inhibitor. It works by inhibiting ACE, an enzyme involved in the renin-angiotensin-aldosterone system. By blocking ACE, Ramipril reduces the production of angiotensin II, a potent vasoconstrictor, leading to vasodilation and decreased aldosterone secretion. These effects result in decreased peripheral resistance and blood volume, thereby reducing blood pressure and improving cardiac function.
Pharmacological Properties
Hartil Tablets exert antihypertensive, cardioprotective, and vasodilatory effects. Ramipril’s ACE inhibitory action leads to decreased vasoconstriction, sodium retention, and aldosterone secretion. These properties contribute to its efficacy in managing hypertension, heart failure, and reducing cardiovascular risks.
Indications for Use
Hartil Tablets are indicated for the treatment of hypertension to lower blood pressure, heart failure to improve cardiac function, and for the prevention of stroke and heart attack in high-risk patients.
Contraindications
- Patients with a known hypersensitivity to Ramipril or any other component of the product should not use Hartil Tablets.
- Use of Hartil Tablets is contraindicated during pregnancy and lactation due to potential risks to the fetus or infant.
- Individuals with severe renal impairment should avoid Hartil Tablets as renal function may further deteriorate.
- Patients with a history of angioedema associated with previous ACE inhibitor use should not take Hartil Tablets.
Side Effects
Common side effects of Hartil Tablets may include dizziness, cough, hypotension, and hyperkalemia. Rare but serious side effects may include angioedema, renal impairment, and neutropenia. Patients should seek medical attention if they experience any severe or persistent side effects while taking Hartil Tablets.
Usage Instructions
Hartil Tablets are for oral administration and should be taken once daily, preferably at the same time each day. The initial recommended dose is 5 mg, which may be adjusted by a healthcare provider based on the individual’s response. Patients should not exceed the prescribed dose without consulting their healthcare provider.
Benefits Compared to Analogues
Hartil Tablets offer the advantage of once-daily dosing convenience compared to some ACE inhibitors that require multiple daily doses. Additionally, the cardioprotective effects of Ramipril make it a preferred choice for patients with heart failure or at risk of cardiovascular events.
Suitable Patient Groups
Hartil Tablets are suitable for adult patients with hypertension, heart failure, or high cardiovascular risk. The dosage may need adjustment in elderly patients or those with renal impairment. Pediatric use of Hartil Tablets should be determined by a healthcare provider based on individual considerations.
Storage and Shelf Life
Hartil Tablets should be stored at room temperature away from moisture and heat. The shelf life of the product is typically indicated on the packaging and should be checked before use.
Packaging Description
Hartil Tablets are typically packaged in blister packs containing 28 tablets. The packaging is designed to protect the tablets from environmental factors and maintain their stability until use.
