Description
Hipotel (Telmisartan) Tablets 40 mg. №28
Composition
Telmisartan 40 mg
Mechanism of Action
Telmisartan is an angiotensin II receptor blocker (ARB) that selectively blocks the angiotensin II receptor type 1 (AT1). By blocking the effects of angiotensin II, telmisartan inhibits vasoconstriction and the release of aldosterone, leading to vasodilation and decreased blood pressure.
Pharmacological Properties
Telmisartan exhibits high affinity and selectivity for the AT1 receptor. It does not exhibit any partial agonist activity and has a long duration of action. Telmisartan is well-absorbed orally and undergoes minimal first-pass metabolism. The drug is highly protein-bound and excreted primarily via the feces.
Indications for Use
Hipotel tablets are indicated for the treatment of hypertension to lower blood pressure in adult patients.
Contraindications
Avoid Hipotel tablets in patients who are pregnant, have a history of angioedema with previous use of ACE inhibitors, or have severe liver disease. Use with caution in patients with renal impairment.
Side Effects
Common side effects of Hipotel tablets may include dizziness, hypotension, hyperkalemia, and fatigue. Rare but serious side effects may include renal impairment, angioedema, and hepatic failure. Patients should seek medical attention if they experience any severe or persistent side effects.
Usage Instructions
Adults: The recommended dosage of Hipotel tablets is 40 mg once daily. Dosage adjustments may be made by a healthcare provider based on individual patient needs. The tablets should be taken orally with or without food. It is important not to exceed the prescribed dose.
Benefits Compared to Analogs
Hipotel tablets offer the advantage of once-daily dosing convenience compared to some other antihypertensive medications. Telmisartan has a long half-life, allowing for sustained blood pressure control with fewer daily administrations. Additionally, telmisartan has a lower risk of causing dry cough compared to ACE inhibitors.
Suitable Patient Groups
Hipotel tablets are suitable for adult patients with hypertension who require blood pressure management. The medication is generally well-tolerated and can be used in various patient populations, including the elderly. However, special consideration should be given to patients with renal impairment or other comorbidities.
Storage and Shelf Life
Store Hipotel tablets at room temperature away from moisture and heat. Keep the medication in its original packaging to protect it from light. Check the expiration date on the packaging and do not use the tablets after the specified shelf life.
Packaging Description
Hipotel tablets are available in packs containing 28 tablets. Each tablet is film-coated for oral administration. The packaging is designed to ensure the integrity and stability of the tablets until the expiration date.
