Description
Clevazol (Clindamycin, Miconazole) Vaginal Cream 20 g Tube №1
Ingredients
Active ingredients: Clindamycin phosphate, Miconazole nitrate.
Other ingredients: Benzyl alcohol, cetostearyl alcohol, sorbitan stearate, polysorbate 60, propylene glycol, purified water.
Mechanism of Action
Clevazol combines the antibacterial properties of Clindamycin with the antifungal effects of Miconazole. Clindamycin inhibits bacterial protein synthesis by binding to the 50S subunit of the ribosome, while Miconazole disrupts the fungal cell membrane by inhibiting ergosterol synthesis.
Pharmacological Properties
The dual action of Clindamycin and Miconazole in Clevazol provides broad-spectrum coverage against susceptible strains of Candida and bacteria causing vaginal infections. Clindamycin’s antibacterial activity and Miconazole’s antifungal properties work synergistically to eliminate pathogens.
Indications for Use
Indicated for: Treatment of vaginal infections caused by susceptible strains of Candida or bacterial vaginosis.
Contraindications
Contraindications: Avoid use in individuals with a known hypersensitivity to any component of the product. It is contraindicated in patients with a history of inflammatory bowel disease.
Side Effects
Common side effects may include local irritation, itching, burning, or rash at the application site. If severe irritation or allergic reactions occur, discontinue use and seek medical advice.
Usage Instructions
Dosage: Apply a thin layer of the cream intravaginally using the applicator once daily at bedtime for 7 consecutive days. Consult a healthcare provider for specific instructions.
Directions: Wash hands before and after application. Insert the applicator gently into the vagina and press the plunger to release the cream. Avoid contact with eyes.
Benefits Compared to Analogues
Clevazol offers the advantage of combining two active ingredients with complementary mechanisms of action, providing a more comprehensive approach to treating vaginal infections compared to single-agent therapies.
Suitable Patient Groups
Clevazol is suitable for use in adult women. Consult a healthcare provider for guidance on use in specific patient populations such as children, pregnant women, or the elderly.
Storage and Shelf Life
Store the cream at room temperature away from moisture and heat. Check the expiration date on the packaging and do not use the product if expired.
Packaging Description
Clevazol is supplied in a 20 g tube for intravaginal application. Each tube is designed for single-patient use and comes with an applicator for convenient and accurate dosing.
Scientific Evidence
Clinical studies have shown the efficacy of Clevazol (Clindamycin, Miconazole) Vaginal Cream in treating vaginal infections. The combination therapy has demonstrated effectiveness in resolving symptoms and eradicating pathogens, supporting its use in clinical practice.
Additional Information
Complete the full course of treatment as prescribed to ensure the infection is fully cleared. Avoid sexual activity during treatment to prevent reinfection. Consult a healthcare provider if symptoms persist or worsen. Adhere to proper storage conditions to maintain the cream’s stability and effectiveness.
