Description
Clopixol-depo (Zuclopenthixol) Solution for Injections Ampoules 200 mg. 1ml. №10
Ingredients:
Each ampoule contains 200 mg of zuclopenthixol in 1ml solution for injections.
Mechanism of Action:
Zuclopenthixol exerts its antipsychotic effects by blocking dopamine receptors in the brain, thus modulating neurotransmission and reducing psychotic symptoms.
Pharmacological Properties:
Zuclopenthixol, a thioxanthene derivative, acts as a potent antagonist at dopamine D1 and D2 receptors, leading to its antipsychotic properties.
Indications for Use:
Clopixol-depo is indicated for the treatment of schizophrenia and other psychoses. It is effective in managing symptoms such as hallucinations, delusions, and disorganized thinking.
Contraindications:
Do not use Clopixol-depo in patients with known hypersensitivity to zuclopenthixol or any of the ingredients. It is contraindicated in patients with CNS depression, comatose states, and blood dyscrasias.
Side Effects:
Common side effects of Clopixol-depo may include extrapyramidal symptoms, sedation, anticholinergic effects, and metabolic changes. Monitoring for these adverse reactions is essential during treatment.
Usage Instructions:
Administration of Clopixol-depo should be performed by a healthcare professional. The recommended dose is typically administered via deep intramuscular injection. Injection sites should be alternated to prevent local irritation.
Benefits Compared to Analogues:
Clopixol-depo offers a long-acting formulation that enhances medication adherence and long-term treatment outcomes in patients with schizophrenia. Compared to other antipsychotics, it demonstrates similar efficacy with potentially fewer side effects, improving the overall tolerability profile.
Suitable Patient Groups:
Clopixol-depo is suitable for adult patients with schizophrenia or other psychotic disorders. Special caution is advised when prescribing to elderly individuals or patients with comorbid medical conditions. It is not recommended for children.
Storage and Shelf Life:
Store Clopixol-depo in a cool, dry place away from light. Do not freeze. Check the expiration date on the packaging and do not use the product beyond this date.
Packaging Description:
Clopixol-depo is supplied in ampoules containing 200 mg of zuclopenthixol in 1ml solution. Each package includes 10 ampoules for multiple doses.
Clinical Evidence and Proven Effectiveness:
Studies have shown that zuclopenthixol, the active ingredient in Clopixol-depo, effectively reduces positive symptoms of schizophrenia, such as hallucinations and delusions. Clinical trials have demonstrated the efficacy and safety of Clopixol-depo in the management of psychotic disorders.
