Description
Clotrimazol (Clotrimazolum) Solution 1% 25 ml
Composition
Clotrimazol (Clotrimazolum) 1% solution
Mechanism of Action
Pharmacological Properties: Clotrimazol inhibits the synthesis of ergosterol, a crucial component of fungal cell membranes. This inhibition disrupts the membrane structure, leading to increased permeability and eventual fungal cell death, effectively treating the infection.
Indications for Use
Indications: Clotrimazol solution is indicated for the treatment of fungal skin infections, including athlete’s foot, jock itch, and ringworm.
Contraindications
Contraindications: Do not use Clotrimazol solution if allergic to clotrimazol or any other components in the solution. Avoid contact with eyes.
Side Effects
Side Effects: Common side effects may include skin irritation, burning, or redness at the application site. If any severe reactions occur, discontinue use and consult a healthcare professional.
Usage Instructions
Directions: Clean and dry the affected area before applying a thin layer of the solution 2-3 times daily or as directed by a healthcare provider. Wash hands after application. Do not cover the treated area unless advised by a healthcare professional.
Benefits Compared to Analogues
Comparative Effectiveness: Clotrimazol solution is highly effective against various fungal infections due to its broad-spectrum antifungal activity. It is often preferred for its minimal side effects compared to other antifungal agents.
Suitable Patient Groups
Patient Groups: Clotrimazol solution is suitable for adults, children, and the elderly. Dosage adjustments may be necessary based on individual patient needs.
Storage and Shelf Life
Storage: Store the solution at room temperature, away from moisture and heat. Keep out of reach of children. Check the expiration date before use.
Packaging Description
The Clotrimazol solution is packaged in a 25 ml bottle for topical application. The packaging is designed to maintain product integrity and prevent contamination.
Clinical Evidence and Proven Effectiveness
Clotrimazol is a well-established antifungal medication with proven efficacy in treating superficial fungal infections. Studies have shown that clotrimazol effectively inhibits fungal growth by disrupting cell membranes. Research published in the Journal of the American Academy of Dermatology has further supported the effectiveness of clotrimazol in managing fungal infections.
