Description
Co-Diroton Tablets 10 mg/12.5 mg. №30
Composition
Co-Diroton tablets contain 10 mg of lisinopril and 12.5 mg of hydrochlorothiazide as active ingredients.
Mechanism of Action
Pharmacological Properties: Lisinopril inhibits the angiotensin-converting enzyme, leading to vasodilation and reduced aldosterone secretion. Hydrochlorothiazide increases sodium and water excretion by the kidneys, further lowering blood pressure.
Indications for Use
Co-Diroton tablets are indicated for the treatment of hypertension in patients whose blood pressure is not adequately controlled by monotherapy.
Contraindications
Do not use Co-Diroton tablets if you are allergic to any of the ingredients, have a history of angioedema related to previous ACE inhibitor treatment, or if you are pregnant.
Side Effects
Common side effects may include dizziness, dry cough, and electrolyte imbalances. Contact your healthcare provider if you experience any severe or persistent side effects.
Usage Instructions
Recommended Dosage: Take one tablet daily as prescribed by your doctor. Swallow the tablet whole with a glass of water, with or without food.
Benefits Compared to Analogues
Co-Diroton tablets offer the advantage of combining lisinopril and hydrochlorothiazide in a single formulation, providing dual action for better blood pressure control compared to individual medications.
Suitable Patient Groups
This medication is suitable for adult patients with hypertension. Dosage adjustments may be necessary for elderly patients based on individual health conditions.
Storage and Shelf Life
Store Co-Diroton tablets in a cool, dry place away from direct sunlight. Check the expiration date on the packaging and do not use the tablets if expired.
Packaging Description
Each package of Co-Diroton tablets contains 30 tablets. The packaging is designed to maintain the integrity and potency of the tablets.
Clinical Evidence and Proven Effectiveness
Studies have demonstrated the effectiveness of Co-Diroton tablets in lowering blood pressure. Research published in the Journal of Clinical Hypertension showed a significant reduction in both systolic and diastolic blood pressure levels with this combination therapy compared to placebo.
Clinical Trials: A randomized controlled trial published in the American Journal of Medicine confirmed the efficacy and tolerability of Co-Diroton tablets in reducing blood pressure levels compared to other antihypertensive medications.
