Description
Co-Diroton Tablets 20 mg/12.5 mg. №30
Ingredients
Co-Diroton tablets contain 20 mg of enalapril maleate and 12.5 mg of hydrochlorothiazide as active ingredients.
Mechanism of Action
Enalapril inhibits the angiotensin-converting enzyme, leading to vasodilation and reduced blood pressure. Hydrochlorothiazide acts as a diuretic, promoting the excretion of sodium and water, further lowering blood pressure.
Pharmacological Properties
Co-Diroton tablets combine the antihypertensive effects of enalapril and hydrochlorothiazide, providing a synergistic approach to managing hypertension.
Indications for Use
Co-Diroton tablets are indicated for the treatment of hypertension in patients requiring dual therapy for optimal blood pressure control.
Contraindications
Do not use Co-Diroton tablets if you are allergic to any of the ingredients, have a history of angioedema related to ACE inhibitors, or if you are pregnant.
Side Effects
Common side effects of Co-Diroton may include dizziness, dry cough, electrolyte imbalances, and hypotension. Contact your healthcare provider if you experience any adverse reactions.
Usage Instructions
The recommended dosage of Co-Diroton is one tablet once daily. Take the tablet whole with a glass of water, without crushing or chewing it.
Benefits Compared to Analogues
Co-Diroton offers the advantage of dual therapy in a single tablet, simplifying the treatment regimen for patients requiring both enalapril and hydrochlorothiazide.
Suitable Patient Groups
Co-Diroton can be used in adult patients with hypertension who require combination therapy. Dosage adjustments may be necessary for elderly patients or those with renal impairment.
Storage and Shelf Life
Store Co-Diroton tablets in a cool, dry place away from direct sunlight. Check the expiration date on the packaging and do not use the product beyond the stated shelf life.
Packaging Description
Co-Diroton tablets are typically packaged in blister packs of 30 tablets each, ensuring convenient and accurate dosing for the prescribed duration.
Clinical Evidence and Proven Effectiveness
Studies have shown that the combination of enalapril and hydrochlorothiazide in Co-Diroton tablets effectively lowers blood pressure in hypertensive patients. Research published in the Journal of Clinical Hypertension demonstrated the superior efficacy of combination therapy over monotherapy.
Additional Information
Monitor your blood pressure regularly while taking Co-Diroton tablets. Inform your healthcare provider of any side effects or concerns. Avoid alcohol consumption while on this medication.
