Description
Corinfar UNO (nifedipine) Tablets with Prolonged Release 40 mg. №100
Composition:
Each tablet contains 40 mg of nifedipine with prolonged release.
Mechanism of Action:
Nifedipine, a calcium channel blocker, acts by relaxing blood vessels, leading to decreased blood pressure and enhanced blood flow to the heart.
Pharmacological Properties:
Corinfar UNO contains nifedipine, which exerts its therapeutic effects by inhibiting calcium ion influx across cell membranes in cardiac and smooth muscle cells, resulting in vasodilation and reduced myocardial contractility.
Indications for Use:
Corinfar UNO is indicated for the management of hypertension (high blood pressure) and angina (chest pain).
Contraindications:
Avoid using Corinfar UNO if you have hypotension (low blood pressure), a history of myocardial infarction (heart attack), or a known hypersensitivity to nifedipine.
Side Effects:
Common side effects of Corinfar UNO may include dizziness, facial flushing, or peripheral edema. Contact your healthcare provider promptly if you encounter severe adverse reactions.
Usage Instructions:
The typical dosage regimen involves taking one tablet orally once daily. Swallow the tablet whole with a glass of water; do not crush or chew it.
Benefits Compared to Analogues:
Corinfar UNO offers the advantage of once-daily dosing due to its prolonged-release formulation, ensuring sustained efficacy and improved patient compliance compared to immediate-release formulations.
Suitable Patient Groups:
Corinfar UNO is suitable for adult patients with hypertension or angina. Dosage adjustments may be necessary for specific populations such as the elderly or those with hepatic impairment; consult a healthcare professional for personalized recommendations.
Storage Conditions and Shelf Life:
- Store Corinfar UNO at room temperature, protecting it from moisture and excessive heat.
- Check the expiration date on the packaging and do not use the product beyond its shelf life.
Packaging Description:
Each package of Corinfar UNO contains 100 tablets of 40 mg nifedipine with prolonged release, ensuring an adequate supply for continuous therapy.
Scientific Evidence:
Numerous studies have validated the efficacy and safety of nifedipine in the treatment of hypertension and angina. Notably, a randomized controlled trial published in the Journal of the American Medical Association demonstrated the blood pressure-lowering effects of nifedipine with favorable tolerability. Additionally, a study in the European Heart Journal emphasized the role of nifedipine in reducing angina frequency and enhancing exercise capacity in patients with stable angina.
