Description
Coronal-10 (Bisoprolol) Coated Tablets 10 mg. №60
Composition
Each coated tablet contains 10 mg of bisoprolol fumarate as the active ingredient.
Mechanism of Action
Bisoprolol, a selective beta-blocker, blocks the action of natural substances like epinephrine in the body, leading to decreased heart rate, blood pressure, and cardiac strain.
Pharmacological Properties
Bisoprolol exerts its effects by selectively targeting beta-1 adrenergic receptors, resulting in reduced sympathetic activity on the heart and blood vessels.
Indications for Use
Coronal-10 (Bisoprolol) tablets are indicated for the management of hypertension and specific cardiac conditions.
Contraindications
Avoid Coronal-10 if there is a history of hypersensitivity to bisoprolol or other beta-blockers. Patients with certain cardiac conditions may also be contraindicated.
Side Effects
Common side effects of Coronal-10 include fatigue, dizziness, and peripheral coldness. Severe adverse reactions should prompt immediate medical attention.
Usage Instructions
The typical dosage regimen involves taking one tablet daily, preferably with water, without crushing or chewing the tablet. Dosage adjustments should only be made under healthcare provider guidance.
Benefits Compared to Analogues
Coronal-10 offers advantages over other beta-blockers due to its selective beta-1 receptor activity, potentially resulting in fewer side effects related to beta-2 receptor blockade.
Suitable Patient Groups
Coronal-10 can be prescribed to a wide range of patient populations, including adults, elderly individuals, and selected pediatric cases under appropriate medical supervision.
Storage and Shelf Life
Store Coronal-10 in a cool, dry place away from direct sunlight. Adhere to the specified expiration date to ensure product efficacy.
Packaging Description
Coronal-10 (Bisoprolol) tablets are available in a package containing 60 coated tablets. The packaging is designed to maintain product integrity and facilitate convenient dosing.
Clinical Evidence and Proven Effectiveness
Clinical studies have demonstrated the efficacy of bisoprolol in reducing cardiovascular events in heart failure patients. Notably, research in the European Journal of Heart Failure highlighted the mortality and hospitalization benefits associated with bisoprolol use.
Additional Information
Regular monitoring of blood pressure and heart rate is crucial during Coronal-10 therapy to optimize treatment outcomes. Consultation with a healthcare professional is recommended before initiating or discontinuing this medication.
