Description
Cortineff (Fludrocortisone Acetate) Tablets 0.1 mg. №20
Ingredients
Active ingredient: Fludrocortisone acetate 0.1 mg per tablet.
Mechanism of Action
Fludrocortisone acetate is a synthetic corticosteroid that primarily acts by enhancing sodium reabsorption in the distal tubules of the kidney. This action leads to increased blood volume and improved blood pressure in patients with adrenal insufficiency.
Pharmacological Properties
Fludrocortisone acetate exerts mineralocorticoid activity, promoting sodium retention and potassium excretion.
Indications for Use
- Primary adrenocortical insufficiency (Addison’s disease)
- Salt-losing adrenogenital syndrome
Contraindications
- Hypersensitivity to fludrocortisone acetate
- Systemic fungal infections
Side Effects
Common side effects may include fluid retention, hypertension, and hypokalemia.
Usage Instructions
Dosage: The usual dose is 0.1 to 0.2 mg daily, taken orally.
- Take as directed by your healthcare provider
- Do not exceed the recommended dose
Benefits Compared to Analogues
Cortineff tablets provide effective management of adrenal insufficiency with a well-established safety profile compared to other mineralocorticoids.
Suitable Patient Groups
Appropriate for use in adults, children, and the elderly under medical supervision.
Storage and Shelf Life
Store in a cool, dry place away from sunlight. Check the expiration date on the packaging.
Packaging Description
Cortineff tablets are available in a package containing 20 tablets of 0.1 mg strength.
Clinical Evidence and Proven Effectiveness
Studies have shown that fludrocortisone acetate is effective in managing salt-losing adrenogenital syndrome and primary adrenocortical insufficiency. Clinical trials have demonstrated its efficacy in improving symptoms and quality of life in patients with Addison’s disease.
Additional Information
It is important to monitor blood pressure, electrolyte levels, and weight regularly while taking fludrocortisone acetate to ensure optimal treatment outcomes. Consult your healthcare provider for personalized dosing instructions and potential drug interactions.