Description
Cremgen (Fluocinonide, Gentamicin) Ointment 30 g
Ingredients
Active Ingredients: Fluocinonide, Gentamicin
Mechanism of Action
Fluocinonide is a potent corticosteroid that exerts anti-inflammatory, anti-pruritic, and vasoconstrictive effects by inhibiting the production of inflammatory mediators. Gentamicin, an aminoglycoside antibiotic, works by disrupting bacterial protein synthesis, thereby exerting bactericidal activity against susceptible organisms.
Pharmacological Properties
Cremgen ointment combines the anti-inflammatory and anti-bacterial properties of fluocinonide and gentamicin, respectively. This dual-action formulation effectively alleviates symptoms of corticosteroid-responsive dermatoses complicated by secondary bacterial infections.
Indications for Use
Cremgen ointment is indicated for the relief of inflammatory and pruritic manifestations associated with corticosteroid-responsive dermatoses when complicated by secondary infections caused by gentamicin-susceptible organisms.
Contraindications
Avoid using Cremgen ointment if you have a known allergy to fluocinonide, gentamicin, or any other ingredients in the formulation. Refrain from applying the ointment on the face, underarms, or groin area without medical supervision to prevent potential adverse effects.
Side Effects
Common side effects of Cremgen ointment may include skin irritation, burning, itching, dryness, or redness at the application site. Notify your healthcare provider if you experience severe skin reactions or signs of an allergic response.
Usage Instructions
Apply a thin layer of Cremgen ointment to the affected skin area 2-3 times daily or as directed by a healthcare professional. Ensure the skin is clean and dry before application. Wash your hands thoroughly after applying the ointment and avoid contact with the eyes.
Benefits Compared to Analogues
Cremgen ointment offers a unique combination of potent corticosteroid and antibiotic agents, providing synergistic efficacy in managing inflammatory skin conditions with secondary bacterial infections. The dual-action formula of fluocinonide and gentamicin in Cremgen ointment surpasses the individual therapeutic benefits of each component alone.
Suitable Patient Groups
Cremgen ointment is suitable for adult patients and children over a certain age as determined by a healthcare provider. Use in elderly individuals should be monitored closely due to the potential for increased skin sensitivity and decreased drug metabolism.
Storage and Shelf Life
Store Cremgen ointment at room temperature, away from direct sunlight and moisture. Check the product packaging for the expiry date and do not use the ointment beyond the stated shelf life to ensure optimal effectiveness.
Packaging Description
Cremgen ointment is supplied in a 30 g tube for topical application. The packaging is designed to maintain the stability and integrity of the active ingredients throughout the product shelf life.
Clinical Evidence and Proven Effectiveness
Pharmacological Effects: The combination of fluocinonide and gentamicin in Cremgen ointment provides a dual therapeutic approach against inflammatory skin conditions with secondary bacterial infections, offering comprehensive symptom relief and infection control.
Clinical Trials: Studies have demonstrated the efficacy of Cremgen ointment in treating various dermatoses, including eczema, psoriasis, and contact dermatitis. The synergistic action of fluocinonide and gentamicin has shown superior outcomes compared to monotherapy, highlighting the clinical benefits of this combination formulation.
Additional Information
It is essential to complete the prescribed course of Cremgen ointment to prevent the development of antibiotic resistance. Discontinue use and seek medical advice if you experience any adverse reactions or skin sensitivities. Keep the ointment out of reach of children and consult your healthcare provider or product leaflet for further safety and efficacy details.
