Description
Dalacin (Clindamycin) Vaginal Cream 2% 20 g
Ingredients
Active ingredient: Clindamycin phosphate 2% w/w. Other ingredients: benzyl alcohol, sorbitan monostearate, polysorbate 60, propylene glycol, and purified water.
Mechanism of Action
Clindamycin, a lincosamide antibiotic, inhibits bacterial protein synthesis by binding to the 50S subunit of the bacterial ribosome, leading to the suppression of bacterial growth and eventual eradication of the infection.
Pharmacological Properties
Clindamycin exerts its antibacterial effects by inhibiting protein synthesis in bacteria, thereby reducing the overgrowth of harmful bacteria in the vagina.
Indications for Use
Dalacin Vaginal Cream is indicated for the treatment of bacterial vaginosis (BV) in non-pregnant women.
Contraindications
Do not use Dalacin Vaginal Cream if:
- You have a history of inflammatory bowel disease.
- You have a history of antibiotic-associated colitis.
Side Effects
Common side effects may include vaginal itching, irritation, or discharge. Consult a healthcare provider if these side effects persist or worsen.
Usage Instructions
Adults: Insert one applicatorful (approximately 5 g of cream) intravaginally at bedtime for 7 consecutive days. Wash hands before and after use. Avoid sexual intercourse during treatment.
Benefits Compared to Analogues
Dalacin Vaginal Cream containing clindamycin has been shown to be effective in treating BV by reducing harmful bacterial overgrowth, with comparable or superior efficacy to other antibiotics commonly used for BV treatment.
Suitable Patient Groups
This product is suitable for adult women with bacterial vaginosis. Consult a healthcare provider for appropriate use in special populations such as children, elderly individuals, or pregnant women.
Storage and Shelf Life
Store Dalacin Vaginal Cream at room temperature away from moisture and heat. Check the product packaging for the expiration date and do not use after the specified date.
Packaging Description
Dalacin Vaginal Cream is available in a tube containing 20 g of cream. The packaging should include instructions for use and storage.
Scientific Evidence
Clindamycin, the active ingredient in Dalacin Vaginal Cream, has been studied for its efficacy in treating BV. Clinical trials have shown significant improvements in symptoms such as vaginal discharge, odor, and itching. Comparative studies have demonstrated the effectiveness of clindamycin compared to other antibiotics commonly used for BV treatment.
