Description
Depiofen (Dexketoprofen Trometamol) Coated Tablets 25 mg. №10
Ingredients
Each coated tablet contains 25 mg of dexketoprofen trometamol.
Mechanism of Action
Dexketoprofen trometamol, the active ingredient in Depiofen, is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic, anti-inflammatory, and antipyretic properties. It works by inhibiting the enzyme cyclooxygenase, thereby reducing the production of prostaglandins that cause pain and inflammation.
Pharmacological Properties
Dexketoprofen trometamol exerts its pharmacological effects by specifically targeting the inflammatory process through the inhibition of prostaglandin synthesis, resulting in pain relief and reduction of inflammation.
Indications for Use
Depiofen is indicated for the relief of mild to moderate pain conditions, including headaches, dental pain, menstrual cramps, and musculoskeletal pain.
Contraindications
Avoid using Depiofen if you have a history of allergic reactions to dexketoprofen or other NSAIDs, active peptic ulcers, severe heart failure, or during the third trimester of pregnancy.
Side Effects
Common side effects of Depiofen may include nausea, indigestion, and headache. If you experience signs of an allergic reaction, seek immediate medical attention.
Usage Instructions
The recommended dosage for adults is one tablet every 8 hours as needed. Do not exceed three tablets in 24 hours. Swallow the tablet whole with water and take with food to reduce the risk of gastrointestinal side effects.
Benefits Compared to Analogues
Depiofen offers rapid and effective pain relief with a lower risk of gastrointestinal side effects compared to some other NSAIDs.
Suitable Patient Groups
Depiofen is suitable for adults for the management of mild to moderate pain. It is not recommended for children, the elderly, or individuals with specific contraindications.
Storage and Shelf Life
- Store Depiofen at room temperature away from moisture and heat.
Packaging Description
Depiofen comes in blister packs containing 10 coated tablets of 25 mg each.
Clinical Evidence and Proven Effectiveness
Several studies have demonstrated the efficacy of dexketoprofen trometamol in managing acute pain conditions. For example, a study by Moore et al. (2014) showed that dexketoprofen provided rapid and effective pain relief in patients with postoperative dental pain compared to placebo.
