Description
Deriva S Gel (Adapalene, Clindamycin) – Topical Acne Treatment
Ingredients
Active ingredients: Adapalene, Clindamycin
Mechanism of Action
Deriva S gel combines the actions of Adapalene and Clindamycin to effectively treat acne vulgaris. Adapalene normalizes the differentiation of follicular epithelial cells, reducing microcomedone formation. Clindamycin exhibits antibacterial activity against Propionibacterium acnes, a bacteria involved in acne formation.
Pharmacological Properties
Deriva S gel’s dual benefits include the retinoid-like effects of Adapalene and the antibacterial properties of Clindamycin. This combination targets both the underlying causes of acne and bacterial growth, promoting clearer skin.
Indications for Use
Deriva S gel is indicated for the topical treatment of acne vulgaris. It is suitable for individuals seeking an effective solution for acne management.
Contraindications
Avoid using Deriva S gel if you have a known allergy to Adapalene, Clindamycin, or any other components of the gel formulation. Consult a healthcare provider if unsure about potential allergens.
Side Effects
Common side effects of Deriva S gel may include skin dryness, redness, or peeling. Discontinue use and seek medical advice if severe irritation or allergic reactions occur.
Usage Instructions
Apply a thin layer of Deriva S gel to the affected area once daily in the evening. Prior to application, cleanse the skin thoroughly and avoid contact with sensitive areas such as eyes, mouth, and mucous membranes.
Benefits Over Analogues
Deriva S gel offers a synergistic effect through the combination of Adapalene and Clindamycin, targeting acne from multiple angles. Its efficacy and tolerability have been demonstrated in clinical trials, making it a valuable option for individuals with acne vulgaris.
Suitable Patient Groups
Deriva S gel is suitable for a wide range of patients, including adolescents, adults, and the elderly, who are looking for an effective topical treatment for acne.
Storage and Shelf Life
Store Deriva S gel in a cool, dry place away from direct sunlight. Check the expiration date on the packaging and do not use the product if past the specified shelf life.
Packaging Description
Deriva S gel is available in a 15g tube for convenient topical application. The packaging is designed to maintain the stability and integrity of the active ingredients.
Clinical Evidence and Proven Effectiveness
Studies have shown that Deriva S gel effectively reduces acne lesions and improves skin condition. In a comparative study published in the Journal of Drugs in Dermatology, Deriva S gel demonstrated comparable efficacy to other acne treatments with a favorable safety profile. The dual mechanism of action of Adapalene and Clindamycin makes it a promising option for acne management.
