Description
Detralex Coated Tablets 1000 mg. №30
Composition
Detralex tablets contain 1000 mg of micronized purified flavonoid fraction (MPFF) composed of 90% diosmin and 10% hesperidin. The tablets also include excipients such as microcrystalline cellulose, gelatin, sodium lauryl sulfate, and talc.
Mechanism of Action
Detralex works by improving venous tone, reducing venous distensibility, and protecting microcirculation. The flavonoids in Detralex act on the venous system, increasing venous tone and decreasing venous distensibility, which helps reduce symptoms associated with venous insufficiency.
Pharmacological Properties
Detralex contains a purified flavonoid fraction that exerts venotonic and vasoprotective effects. It improves venous blood flow, reduces venous stasis, and enhances microcirculation.
Indications for Use
Detralex is indicated for the treatment of symptoms related to chronic venous insufficiency, such as heavy legs, pain, and edema. It is also used in the management of acute hemorrhoidal attacks.
Contraindications
Detralex is contraindicated in individuals with known hypersensitivity to any of the ingredients. It should be used with caution in patients with severe hepatic impairment.
Side Effects
Detralex is generally well-tolerated, with mild side effects such as gastrointestinal disturbances reported infrequently. Rarely, allergic reactions may occur. It is important to seek medical advice if any adverse effects are experienced.
Usage Instructions
The recommended dosage of Detralex is usually one tablet taken twice daily, preferably during meals. The tablets should be swallowed whole with an adequate amount of water. It is essential to follow the instructions provided by a healthcare professional for optimal results.
Benefits Compared to Analogues
Detralex has demonstrated efficacy in improving symptoms of chronic venous insufficiency and hemorrhoids, with comparable effectiveness to other venoactive drugs. Its unique composition of diosmin and hesperidin offers a comprehensive approach to managing venous disorders.
Suitable Patient Groups
Detralex is suitable for a wide range of patient groups, including adults, elderly individuals, and patients with chronic venous insufficiency or hemorrhoids. However, individual dosage adjustments may be necessary based on specific patient characteristics.
Storage and Shelf Life
Detralex should be stored in a cool, dry place away from direct sunlight. The tablets have a shelf life of [insert shelf life here] and should not be used beyond the expiration date printed on the packaging.
Packaging Description
Detralex is available in blister packs containing 30 coated tablets. The packaging is designed to protect the tablets from moisture and external factors that could affect their stability.
Clinical Evidence and Proven Effectiveness
Detralex has been extensively studied for its efficacy in treating chronic venous insufficiency and hemorrhoids. Clinical trials have shown that Detralex significantly improves symptoms such as leg pain, swelling, and cramps. Research published in the Journal of Vascular Research supports the use of MPFF in the management of venous disorders.
