Description
Diacordin (Diltiazem) 120 Retard Tablets with Prolonged Release 120 mg. №30
Composition
Active ingredient: Diltiazem hydrochloride 120 mg.
Other ingredients: lactose monohydrate, hypromellose, colloidal anhydrous silica, magnesium stearate.
Mechanism of Action
Diltiazem, a calcium channel blocker, inhibits the influx of calcium ions across cardiac and smooth muscle cells. This leads to vasodilation, decreased peripheral resistance, reduced myocardial oxygen demand, and improved oxygen delivery to the heart muscle.
Pharmacological Properties
Diacordin 120 Retard Tablets exhibit vasodilator effects by relaxing blood vessels, thereby increasing blood supply and oxygen to the heart. The medication reduces peripheral resistance, aiding in the management of hypertension and angina.
Indications for Use
Diacordin 120 Retard Tablets are indicated for the treatment of hypertension (high blood pressure) and chronic stable angina (chest pain).
Contraindications
Avoid using Diacordin 120 Retard Tablets if you have a known hypersensitivity to diltiazem or any of the excipients. Patients with sick sinus syndrome, severe bradycardia, or hypotension should also refrain from taking this medication.
Side Effects
Common side effects of Diacordin 120 Retard Tablets may include dizziness, headache, edema, and constipation. Consult your healthcare provider if any adverse reactions occur.
Usage Instructions
Take one Diacordin 120 Retard Tablet daily, swallowed whole with water, preferably in the morning. Do not crush or chew the tablet. Follow the dosage prescribed by your healthcare provider and seek medical advice for any adjustments.
Benefits Compared to Analogues
Diacordin 120 Retard Tablets offer effective management of hypertension and angina with the convenience of once-daily dosing and prolonged release formulation, ensuring sustained therapeutic effects.
Suitable Patient Groups
Diacordin 120 Retard Tablets are suitable for adult patients with hypertension and chronic stable angina. Dosage adjustments may be necessary for elderly individuals based on individual health conditions.
Storage and Shelf Life
Store Diacordin 120 Retard Tablets in a cool, dry place away from direct sunlight. Check the expiry date on the packaging and do not use the medication if past the shelf life.
Packaging Description
Diacordin 120 Retard Tablets are available in a pack of 30 tablets, each containing 120 mg of diltiazem hydrochloride. The packaging is designed to maintain the integrity and potency of the medication.
Clinical Evidence and Proven Effectiveness
Clinical studies have shown that diltiazem effectively reduces blood pressure and improves symptoms of angina pectoris. Research published in the Journal of the American College of Cardiology demonstrated a significant decrease in angina attacks frequency and improved exercise tolerance in stable angina patients.
