Description
Diaformin SR (Metformin) Tablets with Prolonged Release 1000 mg. №60
Composition
Each tablet contains: Metformin Hydrochloride 1000 mg.
Mechanism of Action
Metformin, the active ingredient in Diaformin SR, works by decreasing glucose production in the liver and improving insulin sensitivity in peripheral tissues.
Pharmacological Properties
Diaformin SR is a prolonged-release formulation of metformin, providing a steady release of the medication throughout the day.
Indications for Use
Indicated for the treatment of type 2 diabetes mellitus in adults, especially in overweight patients when dietary management and exercise alone are insufficient for glycemic control.
Contraindications
Contraindicated in patients with renal impairment, acute or chronic metabolic acidosis, and hypersensitivity to metformin.
Side Effects
Common side effects may include gastrointestinal disturbances such as nausea, vomiting, and diarrhea. In rare cases, metformin may cause lactic acidosis.
Usage Instructions
Recommended dosage: The usual starting dose is 500 mg or 850 mg once daily with meals. Dosage adjustments should be made based on blood glucose levels. Swallow the tablets whole with a full glass of water; do not crush or chew.
Benefits Compared to Analogues
The prolonged-release formulation of Diaformin SR offers the advantage of once-daily dosing, potentially reducing gastrointestinal side effects compared to immediate-release formulations.
Suitable Patient Groups
Diaformin SR is suitable for adults with type 2 diabetes. Dosage adjustments may be necessary for elderly patients or those with renal impairment.
Storage Conditions and Shelf Life
Store Diaformin SR tablets in a cool, dry place away from direct sunlight. Check the expiry date on the packaging and do not use after the stated shelf life.
Packaging Description
Diaformin SR tablets are supplied in packs of 60 tablets.
Clinical Evidence and Proven Effectiveness
Metformin has been extensively studied in clinical trials, demonstrating its effectiveness in lowering blood glucose levels and reducing the risk of diabetes-related complications. Research published in the Journal of Clinical Investigation has highlighted the positive effects of metformin on hemoglobin A1c levels and overall glycemic control.
