Description
Diapirid (Glimepiride) Tablets 3 mg. №30
Composition
Active ingredient: Glimepiride 3 mg.
Other ingredients: Microcrystalline cellulose, lactose monohydrate, povidone, sodium starch glycolate, and magnesium stearate.
Mechanism of Action
Glimepiride, a sulfonylurea, increases insulin release from the pancreas, leading to decreased blood glucose levels.
Pharmacological Properties
Glimepiride acts by binding to specific receptors on pancreatic beta cells, stimulating insulin secretion in a glucose-dependent manner.
Indications for Use
Diapirid tablets are indicated for the management of type 2 diabetes mellitus when lifestyle interventions alone are insufficient.
Contraindications
Avoid using Diapirid tablets in individuals with a known hypersensitivity to glimepiride or other sulfonylureas.
Side Effects
Common side effects may include hypoglycemia, nausea, and allergic reactions. Consult a healthcare provider for a complete list of adverse effects.
Usage Instructions
Take Diapirid tablets as directed by a healthcare professional. Swallow the tablet whole with water. The initial dose is typically 1 to 2 mg once daily, with adjustments based on blood glucose levels.
Benefits Compared to Analogues
Studies suggest that glimepiride offers similar efficacy and safety to other sulfonylureas in managing blood glucose levels in patients with type 2 diabetes.
Suitable Patient Groups
Diapirid tablets are suitable for adult patients with type 2 diabetes. Dosage adjustments may be necessary for elderly individuals or those with hepatic or renal impairment.
Storage and Shelf Life
Store Diapirid tablets in a cool, dry place away from direct sunlight. Check the packaging for the expiration date and do not use after the specified date.
Packaging Description
Diapirid tablets are available in a pack of 30 tablets, each containing 3 mg of glimepiride. The packaging is designed to maintain product integrity and protect the tablets from environmental factors.
Clinical Evidence and Proven Effectiveness
Scientific studies have demonstrated the efficacy of glimepiride in improving glycemic control in patients with type 2 diabetes. Research published in the Journal of Diabetes Research highlighted the significant reduction in HbA1c levels with glimepiride use compared to placebo.
Comparative effectiveness studies have shown that glimepiride is comparable to other sulfonylureas in managing blood glucose levels. A meta-analysis featured in the Journal of Clinical Pharmacy and Therapeutics concluded that glimepiride exhibits similar efficacy and safety profiles to its counterparts.
