Description
Dimaril (Glimepiride) Tablets 3 mg. №60
Composition
Active Ingredient: Glimepiride 3 mg.
Other Ingredients: Lactose monohydrate, microcrystalline cellulose, povidone, and magnesium stearate.
Mechanism of Action
Pharmacological Properties: Glimepiride stimulates the release of insulin from pancreatic beta cells, thereby lowering blood glucose levels. It also improves insulin sensitivity in peripheral tissues.
Indications for Use
Dimaril tablets are indicated for the treatment of type 2 diabetes mellitus when diet, exercise, and weight reduction alone are not sufficient.
Contraindications
Do not use Dimaril tablets in patients with a history of hypersensitivity to glimepiride or other sulfonylureas.
Side Effects
Common side effects may include hypoglycemia, dizziness, and gastrointestinal disturbances. Serious side effects such as severe allergic reactions are rare but possible.
Usage Instructions
Recommended Dosage: The usual starting dose is 1 to 2 mg once daily with breakfast or the first main meal. Dosage adjustments should be made based on blood glucose levels.
Directions: Take Dimaril tablets exactly as prescribed by your healthcare provider. Swallow the tablet whole with a glass of water.
Benefits Compared to Analogues
Dimaril has shown comparable efficacy to other sulfonylureas in managing blood sugar levels in patients with type 2 diabetes. Its once-daily dosing regimen offers convenience and adherence benefits.
Suitable Patient Groups
Dimaril tablets are suitable for adult patients with type 2 diabetes. Dosage adjustments may be necessary for elderly patients or those with hepatic or renal impairment.
Storage and Shelf Life
Store Dimaril tablets in a cool, dry place away from direct sunlight. Check the expiration date on the packaging and do not use the product after it has expired.
Packaging Description
Each package of Dimaril contains 60 tablets of 3 mg strength. The tablets are packed in a blister pack to ensure freshness and protection from external elements.
Scientific Evidence
Glimepiride, the active ingredient in Dimaril tablets, is a sulfonylurea that works by increasing insulin release from the pancreas. Studies have shown that glimepiride effectively lowers blood glucose levels in patients with type 2 diabetes. Research published in the Journal of Diabetes Investigation demonstrated the efficacy of glimepiride in improving glycemic control and reducing HbA1c levels.
Clinical Trials
Clinical trials have shown that glimepiride is as effective as other sulfonylureas in controlling blood sugar levels in patients with type 2 diabetes. A study published in Diabetes Care compared the efficacy and safety of glimepiride with glibenclamide and found similar outcomes in terms of glycemic control.
