Description
Dimaril (Glimepiride) Tablets 4 mg. №60
Composition
Active Ingredient: Glimepiride 4 mg.
Inactive Ingredients: Lactose monohydrate, microcrystalline cellulose, povidone, sodium starch glycolate, and magnesium stearate.
Mechanism of Action
Glimepiride stimulates the release of insulin from pancreatic beta cells and increases peripheral insulin sensitivity, leading to a reduction in blood glucose levels in patients with type 2 diabetes mellitus.
Pharmacological Properties
Glimepiride is a sulfonylurea derivative that acts by binding to ATP-sensitive potassium channels on pancreatic beta cells, resulting in insulin secretion. It also enhances insulin action on target tissues, promoting glucose uptake and utilization.
Indications for Use
Indicated for: Dimaril (Glimepiride) is recommended as an adjunct to diet and exercise to enhance glycemic control in adults diagnosed with type 2 diabetes mellitus.
Contraindications
Contraindications: Dimaril (Glimepiride) should not be administered to individuals with a history of hypersensitivity to sulfonylureas or any of the product’s components.
Side Effects
- Hypoglycemia
- Weight gain
- Gastrointestinal disturbances
- Allergic reactions
Usage Instructions
Dosage: The typical initial dose is 1-2 mg once daily with breakfast or the first main meal. Adjustments in dosage should be based on individual blood glucose levels.
Benefits Compared to Analogues
Dimaril (Glimepiride) offers a more convenient dosing regimen compared to other sulfonylureas, with a lower risk of hypoglycemia and favorable effects on postprandial glucose levels.
Suitable Patient Groups
Dimaril (Glimepiride) is suitable for use in adult patients with type 2 diabetes mellitus. Caution is advised when prescribing to elderly individuals due to the increased risk of hypoglycemia.
Storage and Shelf Life
Store Dimaril (Glimepiride) in a cool, dry place away from direct sunlight. Ensure proper sealing of the packaging to protect from moisture. Check the expiration date before use.
Packaging Description
Each package of Dimaril (Glimepiride) contains 60 tablets of 4 mg strength. The tablets are typically stored in a blister pack or a bottle with a child-resistant cap for safety.
Clinical Evidence and Proven Effectiveness
Pharmacological Effects: Glimepiride’s mechanism of action has been extensively studied and proven effective in lowering blood glucose levels in patients with type 2 diabetes mellitus.
Clinical Trials: Research has shown that Glimepiride significantly improves glycemic control and reduces HbA1c levels. Studies published in reputable journals have demonstrated its efficacy in managing diabetes.
Additional Information
Regular monitoring of blood glucose levels is crucial to optimize treatment outcomes with Dimaril (Glimepiride). Patients should adhere to their prescribed dosage and meal schedules to prevent complications. Consult a healthcare professional for personalized diabetes management advice.
Prioritize open communication with your healthcare provider regarding any concurrent medications or supplements to prevent potential drug interactions with Dimaril (Glimepiride). Report any changes in health status or adverse effects promptly for appropriate evaluation and management.
