Description
Dimedrol (Diphenhydramine) Tablets 50 mg. №10
Composition
Active Ingredient: Each tablet contains Diphenhydramine 50 mg.
Mechanism of Action
Diphenhydramine works by blocking the action of histamine, a key mediator in allergic reactions. It antagonizes the H1 receptor, thereby preventing histamine-induced symptoms.
Pharmacological Properties
Diphenhydramine exhibits antihistaminic effects by inhibiting histamine binding. It also possesses sedative properties due to its ability to cross the blood-brain barrier and act on the central nervous system.
Indications for Use
Dimedrol tablets are indicated for the symptomatic relief of allergies, hay fever, and common cold symptoms, including sneezing, rhinorrhea, and pruritus of the nasal mucosa or throat.
Contraindications
Avoid using Dimedrol tablets if you have a known hypersensitivity to diphenhydramine or are currently on monoamine oxidase inhibitors (MAOIs) due to the risk of drug interactions.
Side Effects
Common side effects of Diphenhydramine may include drowsiness, dry mouth, blurred vision, and urinary retention. In rare cases, it can lead to paradoxical excitation or allergic reactions.
Usage Instructions
Adults: Take 1 tablet orally every 4 to 6 hours as needed, with a maximum of 6 tablets in 24 hours. Children: Consult a healthcare provider for appropriate dosing based on age and weight.
Benefits Compared to Analogues
Dimedrol offers rapid relief from allergic symptoms with a proven safety profile. Its dual antihistaminic and sedative effects make it a versatile option for managing various allergic conditions.
Suitable Patient Groups
Dimedrol is suitable for use in both adult and pediatric populations, with dosing adjustments based on age and individual response. Caution is advised in elderly patients due to the potential for increased sedation.
Storage and Shelf Life
Store Dimedrol tablets in a cool, dry place away from direct sunlight. Check the expiration date on the packaging and do not use the product beyond the stated shelf life.
Packaging Description
Dimedrol tablets are typically packaged in blister packs to ensure individual tablet integrity. Each pack contains 10 tablets, with clear labeling of the active ingredient and dosage strength.
Clinical Evidence and Proven Effectiveness
Diphenhydramine has been extensively studied for its efficacy in managing allergic symptoms. Clinical trials have demonstrated its ability to alleviate itching, sneezing, and nasal congestion effectively. Notably, research published in the Journal of Allergy and Clinical Immunology highlights the antihistaminic properties of diphenhydramine in mitigating allergic manifestations.
