Description

Dinastat (Parecoxib) Powder for Infusions 40 mg, Vial №10

Composition:

Dinastat contains parecoxib as the active ingredient.

Mechanism of Action:

Parecoxib, a prodrug of valdecoxib, inhibits the COX-2 enzyme, reducing inflammatory mediator production and alleviating postoperative pain and inflammation.

Pharmacological Properties:

Parecoxib’s COX-2 inhibitory properties make it effective in managing postoperative pain with a lower risk of gastrointestinal adverse effects compared to traditional NSAIDs.

Indications for Use:

Dinastat is indicated for the treatment of acute postoperative pain.

Contraindications:

Avoid using Dinastat if allergic to parecoxib or other NSAIDs.

Side Effects:

Common side effects may include gastrointestinal disturbances, headache, and dizziness. Monitor patients for adverse reactions.

Usage Instructions:

Reconstitute the powder with the appropriate diluent as directed by a healthcare provider and administer via intravenous infusion. Dosage should be individualized based on the patient’s needs.

Benefits Compared to Analogues:

Parecoxib’s favorable gastrointestinal safety profile compared to traditional NSAIDs makes it a preferred option for postoperative pain management.

Suitable Patient Groups:

Dinastat can be used in various patient populations, including adults, elderly, and non-allergic individuals requiring postoperative pain relief.

Storage Conditions and Shelf Life:

Store Dinastat as per the manufacturer’s instructions. Check the expiration date on the packaging and do not use beyond that date.

Packaging Description:

The product is available in vials containing 40 mg of parecoxib each, with 10 vials per package.

Clinical Evidence and Proven Effectiveness:

Studies have shown that parecoxib effectively manages postoperative pain through COX-2 inhibition. Clinical trials have demonstrated its analgesic efficacy and safety in various surgical settings.