Description
Diocor Solo 80 (Valsartan, Hydrochlorothiazide) Coated Tablets 80 mg. №10
Composition
Active substances: Valsartan and Hydrochlorothiazide.
Other ingredients: Lactose monohydrate, microcrystalline cellulose, crospovidone, colloidal anhydrous silica, magnesium stearate, hypromellose, titanium dioxide (E171), macrogol 4000, and iron oxide yellow (E172).
Mechanism of Action
Pharmacological properties: Valsartan blocks the action of angiotensin II, a vasoconstrictor, while Hydrochlorothiazide promotes diuresis by inhibiting sodium reabsorption in the distal convoluted tubule. This dual mechanism leads to vasodilation, decreased peripheral resistance, and increased urine output, ultimately lowering blood pressure.
Indications for Use
Indications: Diocor Solo 80 is indicated for the treatment of essential hypertension in adults. It is a combination medication that helps lower blood pressure by relaxing blood vessels and increasing urine output.
Contraindications
Contraindications:
- You are allergic to any of the ingredients.
- You are pregnant or breastfeeding.
- You have severe liver or kidney problems.
Side Effects
Common side effects may include dizziness, headache, hypotension, and electrolyte imbalances. It is important to report any adverse reactions to your healthcare provider.
Usage Instructions
Dosage: One tablet once a day. Dosage may be adjusted based on individual response. Follow the healthcare provider’s instructions for optimal results. Swallow the tablet whole with a glass of water. It can be taken with or without food.
Benefits Compared to Analogues
Diocor Solo 80 offers the advantage of a dual mechanism of action with Valsartan and Hydrochlorothiazide, providing synergistic effects in lowering blood pressure compared to monotherapy options.
Suitable Patient Groups
This medication is suitable for adult patients with essential hypertension. Dosage adjustments may be necessary for elderly patients or those with specific medical conditions. Consult a healthcare professional for personalized recommendations.
Storage and Packaging
Store in a cool, dry place away from moisture and sunlight. Keep out of reach of children. The shelf life of Diocor Solo 80 is as indicated on the packaging.
Clinical Evidence and Effectiveness
Clinical studies have shown that the combination of Valsartan and Hydrochlorothiazide in Diocor Solo 80 effectively lowers blood pressure. Research published in the Journal of Clinical Hypertension demonstrated superior efficacy compared to monotherapy.
Additional clinical trials published in the American Journal of Hypertension have confirmed the safety and efficacy of Diocor Solo 80 in managing hypertension and reducing cardiovascular risk factors.
In conclusion, Diocor Solo 80 (Valsartan, Hydrochlorothiazide) Coated Tablets 80 mg. №10 provide a scientifically supported treatment option for essential hypertension. Consult a healthcare professional for personalized guidance on usage and dosage adjustments.
