Description
Diroton (Lisinopril) Tablets 5 mg. №56
Ingredients
Active ingredient: Lisinopril.
Inactive ingredients: microcrystalline cellulose, pregelatinized starch, magnesium stearate, and more.
Mechanism of Action
Lisinopril, an ACE inhibitor, acts by inhibiting the angiotensin-converting enzyme. This inhibition reduces the production of angiotensin II, a potent vasoconstrictor, leading to vasodilation and decreased blood pressure.
Pharmacological Properties
Lisinopril exerts antihypertensive effects by suppressing the renin-angiotensin-aldosterone system. It also demonstrates cardioprotective properties beyond blood pressure control, making it beneficial in various cardiovascular conditions.
Indications for Use
Indicated for: Hypertension, heart failure, and post-myocardial infarction.
Contraindications
Contraindicated in: History of angioedema related to previous ACE inhibitor treatment, pregnancy, and bilateral renal artery stenosis.
Side Effects
Common side effects may include dizziness, lightheadedness, and hypotension. Monitoring blood pressure regularly is crucial during treatment with Diroton.
Usage Instructions
Take Diroton (Lisinopril) tablets 5 mg orally once daily, with or without food, as directed by a healthcare professional. Dosage adjustments should only be made under medical supervision.
Benefits Compared to Analogues
Lisinopril has demonstrated superior efficacy and safety profiles compared to other ACE inhibitors, making it a preferred choice in managing hypertension and cardiovascular conditions.
Suitable Patient Groups
Diroton is suitable for adult patients, including the elderly, with hypertension, heart failure, or post-myocardial infarction, under appropriate medical guidance.
Storage Conditions and Shelf Life
Store Diroton in a cool, dry place, away from direct sunlight. Check the expiration date on the packaging and do not use the product beyond its shelf life.
Packaging Description
Diroton (Lisinopril) tablets 5 mg are packaged in a container with 56 tablets. The packaging should be kept intact and out of reach of children.
Scientific Evidence
Lisinopril has been extensively studied in clinical trials, demonstrating its efficacy in managing hypertension and improving outcomes in heart failure patients. Research supports its role as a cornerstone therapy in cardiovascular medicine.