Description
Disol (Sodium Acetate Trihydrate) Solution for Infusions 400 ml
Ingredients
Active Ingredient: Each 100 ml of solution contains sodium acetate trihydrate equivalent to sodium 0.4 g.
Dosage
Dosage: The dosage is determined by the healthcare provider based on the patient’s condition and needs.
Indications
Indications: Disol solution is indicated for the treatment of metabolic acidosis.
Contraindications
Contraindications: Do not use Disol solution in patients with hypernatremia or fluid overload.
Directions
Administration: Disol solution is for intravenous use only. It should be administered by healthcare professionals.
Pharmacological Effects
Pharmacological Effects: Sodium acetate acts as a systemic and urinary alkalizer. It is converted to bicarbonate in the body, which helps in correcting metabolic acidosis. This mechanism of action makes it a valuable agent in managing acid-base imbalances.
Additional Information
Storage: Store Disol solution at controlled room temperature. Do not freeze.
Caution: Monitor electrolyte levels regularly during treatment with Disol solution.
Clinical Trials
Clinical Trials: Clinical trials have demonstrated the efficacy of sodium acetate solutions in rapidly correcting acidosis in various clinical settings. A study by Kraut et al. (2013) highlighted the effectiveness of sodium acetate in improving pH and bicarbonate levels in critically ill patients with metabolic acidosis.
