Description

Domidon (Domperidone) Coated Tablets 10mg, Pack of 30 Tablets

Ingredients:

Each coated tablet contains 10mg of domperidone.

Dosage:

The recommended dose for adults is 10mg taken 3 to 4 times a day before meals.

Indications:

Domidon tablets are indicated for the relief of symptoms of nausea and vomiting.

Contraindications:

Avoid using Domidon if you have a known hypersensitivity to domperidone or any of the tablet’s ingredients.

Directions for Use:

Swallow the tablets whole with a glass of water. Do not crush or chew the tablets.

Pharmacological Effects:

Domperidone acts as a dopamine antagonist, targeting primarily the D2 and D3 receptor subtypes. By blocking these receptors, domperidone increases the release of acetylcholine, enhancing gastrointestinal motility.

Scientific Evidence:

Domperidone works by blocking dopamine receptors in the brain and gut, increasing stomach and intestinal movement. Studies have shown its effectiveness in treating symptoms of nausea and vomiting, particularly in conditions like gastroparesis.

Clinical Trials and Comparative Effectiveness:

A comparative study in the Journal of Gastroenterology found domperidone to be as effective as metoclopramide in relieving gastroparesis symptoms with fewer side effects. It can be a valuable alternative for patients intolerant to metoclopramide.

Additional Information:

It is crucial to adhere to the prescribed dosage and avoid exceeding the recommended amount to prevent potential side effects. Store Domidon tablets in a cool, dry place away from direct sunlight. Consult your healthcare provider before use, especially if you have underlying medical conditions or take other medications.