Description
Drotaverin Forte Tablets 80 mg. №10
Ingredients:
Each tablet contains 80 mg of Drotaverine hydrochloride.
Mechanism of Action:
Drotaverine is a selective inhibitor of phosphodiesterase 4 (PDE4), which effectively relaxes smooth muscles by inhibiting the hydrolysis of cyclic adenosine monophosphate (cAMP). This mechanism leads to vasodilation and reduced smooth muscle contractions, offering relief from spasms.
Pharmacological Properties:
Drotaverine hydrochloride in Drotaverin Forte tablets acts as a spasmolytic agent, targeting smooth muscle spasms in various conditions.
Indications for Use:
Drotaverin Forte tablets are indicated for the treatment of smooth muscle spasms associated with irritable bowel syndrome, biliary colic, and menstrual cramps.
Contraindications:
Avoid using Drotaverin Forte tablets if you have a known hypersensitivity to Drotaverine or any other components of the formulation.
Side Effects:
Common side effects of Drotaverin Forte tablets may include dizziness and gastrointestinal disturbances. It is advised to adhere to the prescribed dosage and frequency to minimize the risk of adverse effects.
Usage Instructions:
Take one tablet (80 mg) orally up to three times a day. Swallow the tablet whole with a glass of water; do not crush or chew it.
Benefits Compared to Analogues:
Drotaverin Forte tablets offer effective relief from smooth muscle spasms with a well-tolerated profile and minimal side effects compared to other spasmolytic agents.
Suitable Patient Groups:
Drotaverin Forte tablets are suitable for adults, including the elderly, for the management of smooth muscle spasms. Use in children should be under the guidance of a healthcare provider.
Storage Conditions and Shelf Life:
Store Drotaverin Forte tablets in a cool, dry place away from direct sunlight. Check the expiration date on the packaging and do not use the product after the specified shelf life.
Packaging Description:
Drotaverin Forte tablets are available in a package containing 10 tablets, each with 80 mg of Drotaverine hydrochloride.
Scientific Evidence:
Several clinical studies have demonstrated the efficacy of Drotaverin in treating smooth muscle spasms. For instance, a study in the International Journal of Gastroenterology showed that Drotaverin effectively reduced the frequency and intensity of irritable bowel syndrome symptoms compared to a placebo.
Additional Information:
Prior to using Drotaverin Forte tablets, consult a healthcare professional, especially if you have underlying medical conditions or are taking other medications to prevent potential drug interactions.