Description
Dufaston (Dydrogesterone) Coated Tablets 10 mg. №20
Composition
Each coated tablet contains 10 mg of dydrogesterone as the active ingredient.
Mechanism of Action
Dydrogesterone exerts its pharmacological effects through selective binding to progesterone receptors, resulting in modulation of the endometrium and supporting early pregnancy by providing luteal phase support.
Pharmacological Properties
Dydrogesterone demonstrates progestational activity without the androgenic, estrogenic, or corticoid effects associated with other synthetic progestins, making it a unique and well-tolerated therapeutic option.
Indications for Use
Dufaston is indicated for the treatment of menstrual disorders, infertility due to luteal insufficiency, and the prevention of threatened or recurrent miscarriage.
Contraindications
Avoid using Dufaston if you have a known allergy to dydrogesterone or any other components of the tablet. Additionally, individuals with a history of liver disease should not take Dufaston due to potential risks.
Side Effects
Common side effects of Dufaston may include nausea, headache, breast tenderness, and breakthrough bleeding. If you experience any severe or persistent side effects, consult your healthcare provider.
Usage Instructions
The typical dosage regimen involves taking one tablet orally once daily. Adherence to the prescribed dosing schedule is crucial for optimal therapeutic outcomes.
Benefits Compared to Analogues
Dufaston offers a favorable safety profile and efficacy comparable to natural progesterone, distinguishing it from traditional progestins. Its unique pharmacological properties make it a preferred choice for various gynecological conditions.
Suitable Patient Groups
Dufaston is suitable for adult women, including those of reproductive age facing menstrual irregularities, infertility issues, or recurrent miscarriages. It can also be used in specific cases under pediatric or geriatric supervision.
Storage Conditions and Shelf Life
Store Dufaston in a cool, dry place away from direct sunlight. Ensure the tablets are kept out of reach of children. Check the expiration date on the packaging and do not use the product beyond this date.
Packaging Description
Dufaston is available in blister packs containing 20 coated tablets. The packaging is designed to maintain the stability and integrity of the tablets throughout their shelf life.
Clinical Evidence and Proven Effectiveness
Dydrogesterone has been extensively researched, with studies demonstrating its efficacy in managing menstrual disorders and infertility. Notably, clinical trials have shown that Dufaston improves menstrual regularity and enhances pregnancy outcomes in women with progesterone deficiency. The resemblance of dydrogesterone’s pharmacological action to natural progesterone underscores its therapeutic value in gynecological practice.
