Description
Efox Long (Isosorbide Mononitrate) Capsules with Prolonged Release №30
Ingredients:
Each capsule contains: Isosorbide mononitrate 40mg, excipients.
Mechanism of Action:
Isosorbide mononitrate, a nitrate vasodilator, works by relaxing the smooth muscles in blood vessels, leading to vasodilation. This mechanism reduces the heart’s workload by increasing blood flow and oxygen supply to the heart muscle, thereby preventing angina attacks.
Pharmacological Properties:
Efox Long capsules with prolonged release ensure a sustained therapeutic effect due to the gradual release of isosorbide mononitrate over time. This formulation provides continuous nitrate therapy, maintaining consistent blood vessel dilation and angina prevention.
Indications for Use:
Efox Long capsules are indicated for the prophylaxis of angina pectoris in patients requiring nitrate therapy. They are recommended for individuals with stable angina to reduce the frequency and severity of angina attacks.
Contraindications:
Do not administer Efox Long if the patient has hypotension (low blood pressure), severe anemia, or a known hypersensitivity to isosorbide mononitrate. Prior consultation with a healthcare provider is essential before initiating treatment to assess the patient’s suitability for this medication.
Side Effects:
Common side effects of Efox Long may include headache, dizziness, flushing, and hypotension. In rare cases, patients may experience reflex tachycardia or methemoglobinemia. Monitoring for adverse reactions is crucial during treatment.
Usage Instructions:
The recommended dosage of Efox Long is one capsule (40mg) taken orally once daily in the morning. The capsules should be swallowed whole with a sufficient amount of water and should not be crushed or chewed to maintain the prolonged-release formulation’s efficacy.
Benefits Compared to Analogues:
Efox Long offers the advantage of prolonged-release technology, ensuring a steady and continuous therapeutic effect compared to immediate-release formulations. This feature minimizes the need for frequent dosing and provides enhanced convenience for patients requiring nitrate therapy.
Suitable Patient Groups:
Efox Long is suitable for adult patients with stable angina requiring long-term nitrate therapy. Special caution is advised when prescribing to elderly individuals or patients with hepatic impairment to adjust the dosage according to individual needs.
Storage Conditions and Shelf Life:
- Store Efox Long capsules at room temperature (15-30°C) in a dry place away from moisture and heat sources.
- Keep the medication out of reach of children and pets to prevent accidental ingestion.
Packaging Description:
Efox Long capsules are available in a pack of 30 capsules with prolonged release technology. The packaging is designed to maintain product integrity and protect the capsules from environmental factors that may compromise their efficacy.
Clinical Evidence and Proven Effectiveness:
Isosorbide mononitrate, the active ingredient in Efox Long, has demonstrated efficacy in numerous clinical studies for the management of angina pectoris. Prolonged-release formulations, such as Efox Long, have shown to reduce angina symptoms, improve exercise tolerance, and enhance quality of life in patients with stable angina.
