Description
Emanera (Esomeprazole) Enteric Capsules 20 mg. №28
Composition:
Each enteric capsule contains 20 mg of esomeprazole.
Mechanism of Action:
Emanera enteric capsules contain esomeprazole, a proton pump inhibitor that works by reducing the production of stomach acid through inhibition of the H+/K+ ATPase enzyme system in the gastric parietal cells.
Pharmacological Properties:
Esomeprazole exerts its effects by selectively and irreversibly binding to the proton pump, leading to a prolonged inhibition of acid secretion. It has a high bioavailability and a relatively long half-life, allowing for once-daily dosing.
Indications for Use:
Emanera enteric capsules are indicated for the treatment of gastroesophageal reflux disease (GERD), erosive esophagitis, and gastric ulcers in adult patients.
Contraindications:
Do not use Emanera capsules if you have a known hypersensitivity to esomeprazole or any component of the formulation. Consult a healthcare provider before use if you are pregnant, breastfeeding, or have severe hepatic impairment.
Side Effects:
Common side effects of Emanera may include headache, nausea, abdominal pain, and diarrhea. Rare but serious side effects may include severe allergic reactions, Clostridium difficile-associated diarrhea, and vitamin B12 deficiency with long-term use.
Usage Instructions:
Take one 20 mg enteric capsule orally once daily at least one hour before a meal. Swallow the capsule whole with water and do not crush or chew it.
Benefits Compared to Analogues:
Emanera, with its active ingredient esomeprazole, has demonstrated superior efficacy in acid suppression and promoting healing of erosive esophagitis compared to other proton pump inhibitors. Its once-daily dosing regimen offers convenience and improved patient compliance.
Suitable Patient Groups:
Emanera enteric capsules are suitable for use in adult patients including the elderly population. The dosage adjustment is not required based on age alone.
Storage and Shelf Life:
Store Emanera capsules in a cool, dry place away from direct sunlight. The shelf life of the product is mentioned on the packaging and should not be exceeded.
Packaging Description:
Emanera enteric capsules are available in packs of 28 capsules. The packaging is designed to protect the capsules from moisture and ensure their stability during storage.
Clinical Evidence and Proven Effectiveness:
Esomeprazole, the active ingredient in Emanera capsules, has been extensively studied in various clinical trials. Clinical studies have shown that esomeprazole is highly effective in treating acid-related disorders such as GERD, erosive esophagitis, and peptic ulcers.
A study published in the American Journal of Gastroenterology demonstrated the superior efficacy of esomeprazole over other proton pump inhibitors in healing erosive esophagitis and providing symptomatic relief.
Additional Information:
It is crucial to adhere to the prescribed dosage and administration schedule of Emanera capsules to optimize therapeutic outcomes. Inform your healthcare provider about all medications you are currently taking to prevent potential drug interactions.
If you encounter severe or persistent adverse effects while using Emanera capsules, seek immediate medical attention for further evaluation and management.
