Description
Enalapril-HL (Enalapril) Tablets №20
Composition
Each Enalapril-HL tablet contains 20mg of enalapril maleate as the active ingredient, along with other inactive components.
Mechanism of Action
Enalapril, an angiotensin-converting enzyme (ACE) inhibitor, works by inhibiting the conversion of angiotensin I to angiotensin II. This leads to vasodilation, reduced aldosterone secretion, decreased blood pressure, and decreased cardiac workload.
Pharmacological Properties
Enalapril-HL tablets exhibit antihypertensive and cardioprotective properties by blocking the renin-angiotensin-aldosterone system and reducing peripheral resistance.
Indications for Use
- Treatment of hypertension
- Management of heart failure
- Improvement of survival post-myocardial infarction
Contraindications
Avoid Enalapril-HL tablets if:
- Pregnant
- History of angioedema with previous ACE inhibitor use
- Severe kidney disease
Side Effects
Common side effects may include dizziness, cough, hypotension, and hyperkalemia. Consult a healthcare provider for a complete list of adverse reactions.
Usage Instructions
The typical starting dose is 5mg once daily, which can be titrated up to a maximum of 40mg per day based on individual response. Administer Enalapril-HL tablets orally with water, with or without food.
Benefits Compared to Analogues
Enalapril has shown similar efficacy to other ACE inhibitors but may have a lower incidence of cough, making it a favorable choice for patients intolerant to cough-inducing medications.
Suitable Patient Groups
Enalapril-HL tablets are suitable for adults, including elderly patients, and not recommended for use in pregnant women or individuals with severe renal impairment without medical supervision.
Storage and Shelf Life
Store Enalapril-HL tablets in a cool, dry place away from direct sunlight. Check the expiration date on the packaging and do not use after the specified date.
Packaging Description
Enalapril-HL tablets are typically packaged in blister packs or amber glass bottles to protect them from light and moisture, ensuring product stability.
Clinical Evidence and Proven Effectiveness
Enalapril has been extensively studied in clinical trials, demonstrating its efficacy in lowering blood pressure, improving cardiac function, and reducing cardiovascular events in patients with hypertension and heart failure.
If you have any concerns or experience adverse effects while using Enalapril-HL tablets, seek medical advice promptly.
