Description
Encorat (Valproic Acid) Coated Tablets with Prolonged Release 500 mg. №30
Ingredients:
Each coated tablet contains 500 mg of valproic acid.
Mechanism of Action:
Valproic acid exerts its pharmacological effects by increasing the levels of gamma-aminobutyric acid (GABA) in the brain, which has inhibitory effects on neurotransmission. This action helps to prevent abnormal electrical activity in the brain, reducing the occurrence of seizures in epilepsy patients and stabilizing mood in individuals with bipolar disorder.
Pharmacological Properties:
Encorat tablets with prolonged release formulation provide a steady level of medication in the blood, reducing the number of doses needed per day.
Indications for Use:
Encorat tablets are indicated for the treatment of epilepsy, bipolar disorder, and migraine headaches. They work by restoring the balance of certain natural substances in the brain.
Contraindications:
Do not use Encorat if you have liver disease, a urea cycle disorder, or a genetic mitochondrial disorder. It is important to inform your doctor about all medical conditions before starting this medication.
Side Effects:
Common side effects of Encorat may include nausea, dizziness, drowsiness, and weight changes. Contact your healthcare provider if you experience any severe or persistent side effects.
Usage Instructions:
Swallow the tablets whole, do not crush or chew them. The recommended dosage is determined by a healthcare provider based on individual needs. It is typically taken once or twice daily with food to reduce stomach upset.
Benefits Compared to Analogues:
Encorat with prolonged-release formulation offers improved patient compliance and convenience compared to immediate-release formulations. Studies have shown that patients taking prolonged-release valproic acid experienced fewer side effects and better tolerability, leading to improved treatment adherence.
Suitable Patient Groups:
Encorat can be used in various patient groups including adults, children, and the elderly. Dosage adjustments may be necessary based on individual patient characteristics and medical conditions.
Storage and Shelf Life:
Store Encorat tablets in a cool, dry place away from direct sunlight. Keep the medication out of reach of children. Check the expiration date on the packaging and do not use the tablets if expired.
Packaging Description:
Encorat tablets are packed in blister packs of 30 tablets each. The packaging is designed to protect the tablets from moisture and external factors that may affect their stability.
Clinical Evidence and Proven Effectiveness:
Studies have shown that valproic acid, the active ingredient in Encorat, is effective in managing seizures and stabilizing mood in patients with bipolar disorder. Research published in the Journal of Clinical Psychopharmacology demonstrated the efficacy of valproic acid in reducing the frequency of migraine attacks.
