Description
Extencef (Cefepime) Powder for Solution for Injections 1000 mg. №1
Ingredients
Active ingredient: Cefepime. Inactive ingredients may include lactose.
Mechanism of Action
Pharmacological Properties: Cefepime exerts its antibacterial effects by inhibiting the synthesis of bacterial cell walls, leading to cell death. It is particularly effective against Gram-negative bacteria and exhibits stability against beta-lactamases, enhancing its spectrum of activity.
Indications for Use
Indications: Extencef is indicated for the treatment of moderate to severe infections caused by susceptible bacteria.
Contraindications
Contraindications: Do not use Extencef if you are allergic to cefepime or any other cephalosporin antibiotics.
Side Effects
Cefepime may cause side effects such as diarrhea, nausea, vomiting, rash, or allergic reactions. Consult your healthcare provider if you experience any adverse effects.
Usage Instructions
Dosage: The usual adult dose is 1 to 2 grams every 8 to 12 hours, depending on the severity of the infection. Extencef is administered by intravenous or intramuscular injection. Follow the instructions provided by your healthcare provider.
Benefits Compared to Analogues
Extencef has shown efficacy in treating serious bacterial infections with broad-spectrum activity against a wide range of pathogens. Its stability against beta-lactamases enhances its effectiveness compared to some analogues.
Suitable Patient Groups
Extencef is suitable for use in adult patients for the treatment of moderate to severe infections. Dosage adjustments may be necessary for pediatric or elderly patients based on individual factors. Consult a healthcare professional for appropriate dosing in specific patient populations.
Storage and Shelf Life
Store Extencef according to the instructions provided on the packaging. Check the expiration date and do not use the product if expired. Proper storage conditions help maintain the stability and effectiveness of the medication.
Packaging Description
Extencef is available as a powder for solution for injections in a single-dose vial containing 1000 mg of cefepime. Each package contains one vial for administration.
Clinical Evidence and Proven Effectiveness
Clinical Trials: Clinical trials have shown that cefepime is well-tolerated and effective in the treatment of various infections, including pneumonia, urinary tract infections, and intra-abdominal infections. Comparative studies have demonstrated the comparable efficacy of cefepime to other broad-spectrum antibiotics, making it a valuable option in clinical practice.
