Description
Finlepsin (Carbamazepine) Tablets 200 mg. №50
Composition
Active ingredient: Each tablet contains Carbamazepine 200mg.
Mechanism of Action
Carbamazepine, the active component of Finlepsin tablets, functions by stabilizing neuronal membranes and reducing the repetitive firing of action potentials. It exerts its anticonvulsant effects through modulation of voltage-gated sodium channels in the brain.
Pharmacological Properties
Finlepsin tablets belong to the class of antiepileptic drugs known as dibenzazepine derivatives. The pharmacological properties of carbamazepine include anticonvulsant, analgesic, and mood-stabilizing effects. It is rapidly absorbed after oral administration and undergoes hepatic metabolism to active metabolites.
Indications for Use
Indications: Finlepsin tablets are indicated for the management of epilepsy, including both focal and generalized seizures. Additionally, they are prescribed for the treatment of trigeminal neuralgia, a neuropathic pain syndrome characterized by severe facial pain.
Contraindications
Contraindications: Avoid the use of Finlepsin tablets in patients with a history of bone marrow suppression, hypersensitivity to carbamazepine, or known sensitivity to tricyclic compounds. Caution is advised in individuals with a predisposition to cardiac conduction abnormalities.
Side Effects
Common side effects associated with Finlepsin tablets include dizziness, drowsiness, nausea, vomiting, and skin rashes. Rare but serious adverse reactions may include agranulocytosis, aplastic anemia, and hepatic toxicity. Patients should be monitored closely for signs of these complications during treatment.
Usage Instructions
Dosage: The typical initial dose of Finlepsin is 200mg twice daily, with gradual titration as needed based on individual response. Dosage adjustments should be made under medical supervision to achieve optimal seizure control while minimizing side effects.
Advantages Over Analogues
Compared to other antiepileptic medications, Finlepsin has demonstrated efficacy in a broad spectrum of seizure types and has a well-established safety profile in long-term use. Its extended-release formulation allows for convenient once or twice-daily dosing, enhancing patient compliance and reducing the risk of missed doses.
Suitable Patient Groups
Finlepsin tablets are suitable for use in both pediatric and adult populations. Special caution should be exercised when prescribing to elderly patients due to age-related changes in drug metabolism and potential interactions with concomitant medications.
Storage and Shelf Life
Store Finlepsin tablets in a cool, dry place away from direct sunlight. Ensure proper sealing of the packaging to protect the tablets from moisture. Check the expiration date on the blister pack and do not use the product beyond the specified shelf life.
Packaging Description
Each package of Finlepsin tablets contains 50 tablets of 200mg strength. The tablets are typically dispensed in blister packs to maintain their stability and facilitate accurate dosing. The packaging should include detailed information on the product name, dosage, and manufacturer.
Clinical Evidence and Effectiveness
Carbamazepine, the primary therapeutic agent in Finlepsin tablets, has been extensively studied for its efficacy in epilepsy and trigeminal neuralgia. Clinical trials have consistently shown significant reductions in seizure frequency and pain intensity with carbamazepine treatment. Long-term use of Finlepsin has been associated with improved quality of life and functional outcomes in patients with these conditions.
