Description
Flenox (Enoxaparin Sodium) Solution for Injections 2000ME/0.2 ml. №10 Syringe
Ingredients
Active ingredient: Enoxaparin sodium
Dosage
Dosage: The usual dose of Flenox is 2000ME/0.2 ml administered subcutaneously once daily.
Indications
Indications: Flenox is indicated for the prevention of deep vein thrombosis (DVT) in patients undergoing surgery, particularly orthopedic surgery.
Contraindications
Contraindications: Flenox is contraindicated in patients with active major bleeding, hypersensitivity to enoxaparin sodium, or a history of heparin-induced thrombocytopenia.
Directions
Directions: Administer Flenox subcutaneously into the abdomen, alternating sides with each dose. Do not inject into muscle.
Pharmacological Properties
Pharmacological Effects: Enoxaparin sodium, a low molecular weight heparin, works by enhancing the inhibition of factor Xa and thrombin. This anticoagulant effect prevents the formation of blood clots.
Side Effects
Flenox may cause side effects such as bleeding, bruising, or injection site reactions. Patients should be monitored for signs of thrombocytopenia and bleeding complications.
Usage Instructions
For adult patients, the recommended dose is 2000ME/0.2 ml once daily. Dosage adjustments may be necessary based on individual patient factors. Consult a healthcare provider for personalized dosing recommendations.
Benefits Compared to Analogues
Enoxaparin has shown comparable efficacy to unfractionated heparin in preventing DVT but with a lower risk of heparin-induced thrombocytopenia, making it a preferred choice in many clinical scenarios.
Suitable Patient Groups
Flenox is suitable for adult patients undergoing orthopedic surgery or at risk of DVT. Special caution should be exercised in elderly patients and those with renal impairment. Use in children should be determined by a healthcare provider.
Storage and Packaging
Flenox should be stored at controlled room temperature and protected from light. The shelf life of the product is as indicated on the packaging. Each package contains 10 syringes of 2000ME/0.2 ml solution for injections.
Clinical Evidence and Proven Effectiveness
Flenox, containing enoxaparin sodium, has been extensively studied for its efficacy in preventing thrombotic events. Clinical trials have demonstrated the superiority of enoxaparin over unfractionated heparin in reducing the risk of DVT and pulmonary embolism post-surgery.
