Description
Fortum Powder for Solution for Injections 500 mg. №1
Ingredients:
Each vial contains 500 mg of ceftazidime (as pentahydrate).
Mechanism of Action:
Ceftazidime, a third-generation cephalosporin antibiotic, exerts its bactericidal effect by inhibiting bacterial cell wall synthesis, leading to cell death. It has broad-spectrum activity against many Gram-negative bacteria.
Pharmacological Properties:
Fortum, containing ceftazidime, demonstrates excellent penetration into tissues and maintains high concentrations in the lungs, making it effective in severe infections. It is particularly active against Pseudomonas aeruginosa.
Indications for Use:
Fortum is indicated for the treatment of various bacterial infections caused by susceptible strains. This includes lower respiratory tract infections, urinary tract infections, skin and skin structure infections, and intra-abdominal infections.
Contraindications:
Avoid using Fortum in patients with known hypersensitivity to cephalosporins. Caution is recommended in individuals with a history of gastrointestinal diseases, especially colitis.
Side Effects:
Common side effects of Fortum may include diarrhea, nausea, and injection site reactions. Patients should promptly report any severe or persistent adverse effects to their healthcare provider.
Usage Instructions:
The dosage and duration of Fortum therapy should be determined by a healthcare provider. It is typically administered via intravenous infusion or deep intramuscular injection. Completing the full course of treatment is essential even if symptoms improve.
Benefits Compared to Analogues:
Fortum, with ceftazidime as the active ingredient, offers a broad spectrum of activity against Gram-negative bacteria, including Pseudomonas aeruginosa. Its tissue penetration and lung concentration maintenance make it a valuable option for severe infections.
Suitable Patient Groups:
Fortum is generally well-tolerated across different patient populations. Specific dosing adjustments may be necessary for children, the elderly, or individuals with renal impairment. Consult a healthcare provider for personalized recommendations.
Storage and Shelf Life:
Store Fortum as per the manufacturer’s instructions, typically at room temperature away from moisture and light. Check the expiry date on the packaging and do not use expired products.
Packaging Description:
Fortum is available in vials containing 500 mg of ceftazidime (pentahydrate) powder for reconstitution. Each package includes detailed instructions for proper preparation and administration.
Scientific Evidence:
Clinical studies have demonstrated the efficacy of ceftazidime in treating nosocomial pneumonia and febrile neutropenia in cancer patients. Its broad-spectrum activity and tissue penetration make it a valuable therapeutic option in severe infections.
